Physical Sciences and Mathematics Commons^™

Toxicity Reference Values For Chlorophacinone And Their Application For Assessing Anticoagulant Rodenticide Risk To Raptors, Barnett A. Rattner, Katherine E. Horak, Rebecca S. Lazarus, Sandra L. Schultz, Susan Knowles, Benjamin G. Abbo, Steven F. Volker

United States Geological Survey: Staff Publications

Despite widespread use and benefit, there are

growing concerns regarding hazards of second-generation

anticoagulant rodenticides to non-target wildlife which

may result in expanded use of first-generation compounds,

including chlorophacinone (CPN). The toxicity of CPN

over a 7-day exposure period was investigated in American

kestrels (Falco sparverius) fed either rat tissue mechanically-

amended with CPN, tissue from rats fed Rozol bait

(biologically-incorporated CPN), or control diets (tissue

from untreated rats or commercial bird of prey diet)

ad libitum. Nominal CPN concentrations in the formulated

diets were 0.15, 0.75 and 1.5 µg/g food wet weight, and

measured concentrations averaged 94 …