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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Microarray Data Analysis And Classification Of Cancers, Grant Gates Jan 2019

Microarray Data Analysis And Classification Of Cancers, Grant Gates

Williams Honors College, Honors Research Projects

When it comes to cancer, there is no standardized approach for identifying new cancer classes nor is there a standardized approach for assigning cancer tumors to existing classes. These two ideas are known as class discovery and class prediction. For a cancer patient to receive proper treatment, it is important that the type of cancer be accurately identified. For my Senior Honors Project, I would like to use this opportunity to research a topic in bioinformatics. Bioinformatics incorporates a few different subjects into one including biology, computer science and statistics. An intricate method for class discovery and class prediction is …


Equilibrium Structures And Thermal Fluctuations In Interacting Monolayers, Emmanuel Rivera Jan 2019

Equilibrium Structures And Thermal Fluctuations In Interacting Monolayers, Emmanuel Rivera

Williams Honors College, Honors Research Projects

Coherency strains appear in interacting atomic monolayers due to differing bond lengths, which can arise from different materials or geometries. Examples include extended monolayers interacting with a substrate and the interacting walls of a multi-walled carbon nanotube. These strains can induce various equilibrium configurations, which we will analyze by means of a phenomenological model that incorporates forces from bond stretching and bending within each layer and the weak van der Waals interactions connecting the separate layers. We vary the strengths of each interaction to explore their effects on equilibrium structures, and the specific case of a two-walled carbon nanotube is …


Absorption Calculator: A Cross-Platform Application For Portable Data Analysis, Annmarie Kolbl Jan 2019

Absorption Calculator: A Cross-Platform Application For Portable Data Analysis, Annmarie Kolbl

Williams Honors College, Honors Research Projects

Traditional spectrometers are expensive and non-portable, making them inaccessible to the public. This application will be used in conjunction with spectrometer hardware developed by Erie Open Systems. The hardware itself is 3D printed and, in addition to being portable, enables data to be collected easily. The purpose of this project is to create a cross-platform application capable of reading the output from the spectrometer hardware, calculating the absorbance levels of the sample against the control, and recording the data in tables stored on the cloud. The end result will be an application that runs on iOS and Android, and is …