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Full-Text Articles in Physical Sciences and Mathematics
An Improved Method For Spectroscopic Quality Classification, Elizabeth G. Mayer
An Improved Method For Spectroscopic Quality Classification, Elizabeth G. Mayer
Mathematics & Statistics ETDs
Spectral quality classification is a vital step in data cleaning before the
analysis of magnetic resonance spectroscopy (MRS) data can be done. This
analysis compares five methods of quality classification; three of these are
legacy methods, Maudsley et al. (2006), Zhang et al. (2018), and
Bustillo et al. (2020), and two newly created methods that used a random forests
classifier (RFC) to inform their classifications. We found that the random forest
classifier was the most accurate at predicting spectra quality (balanced
accuracy for RF of 88% vs legacy of 70%, 72%, or 72%). A
Random-Forests-Informed Filtering method (RFIFM) for quality …
Surface-Enhanced Raman Spectroscopy For Cocaine Detection, Kiersten Jo Mead
Surface-Enhanced Raman Spectroscopy For Cocaine Detection, Kiersten Jo Mead
Chemistry
The detection of drugs of abuse using Raman spectroscopy is of particular interest to forensic researchers at the moment. Raman spectroscopy is highly specific, fast, non-destructive, and can be adapted for in-situ measurements, making it the ideal forensic technique. Researchers working under the guidance of Doctor Igor Lednev have been able to use UV resonance Raman spectroscopy to detect cocaine in oral fluid without the need for sample pretreatment. They were however unable to detect the cocaine at forensically relevant levels. To overcome this limitation, surface-enhanced Raman spectroscopy (SERS) was used in this proof of concept study for the detection …