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Full-Text Articles in Physical Sciences and Mathematics
Why Your Clothes Could Be Killing You: The Detection Of Bpa In Clothing Using Fluorescence Spectrophotometry, Bella Bevel
Why Your Clothes Could Be Killing You: The Detection Of Bpa In Clothing Using Fluorescence Spectrophotometry, Bella Bevel
Scholars Day Conference
Bisphenol-A, better known as BPA, is a carcinogenic compound found in many plastic-containing products due to its ability to add rigidity and strength to the plastic. However, BPA has been found in a wide variety of products not traditionally thought of as “plastic” including feminine hygiene products, printer receipts, and even clothing. Clothing containing a polyester/spandex blend, common in athletic wear, contains BPA, whereas traditional cotton clothing does not. Using flourospectroscopy, the presence of BPA in these types of clothing was confirmed, as well as measured over time. Strips of clothing containing polyester and spandex blends were submerged in a …
The Mental Health And Developmental Effects Of Bisphenol-A, Maryann Rettig
The Mental Health And Developmental Effects Of Bisphenol-A, Maryann Rettig
Scholars Day Conference
My directed study focuses on the mental health and developmental effects of bisphenol-A (BPA) on individuals in close contact with the chemical product. BPA is an organic chemical produced in large quantities that is used in the production of many polycarbonate plastics, feminine hygiene products, and epoxy resins that coat some metal food cans. Because of it being everywhere, BPA often leaches dermally and orally into the human body. The physical effects of BPA have been known and observed for years. However, its mental health effects specifically are not as commonly known. Therefore, in my directed study I would be …
Combination Chemo-Pdt Ionic Nanomedicines As Enhanced Therapeutics For Cancer, Samantha Macchi
Combination Chemo-Pdt Ionic Nanomedicines As Enhanced Therapeutics For Cancer, Samantha Macchi
Arkansas Women in STEM Conference
Cancer remains as one of the leading causes of death in humans worldwide. Nanotechnology has made great strides in improving treatment for the disease. This work describes a simplistic approach to design self-assembled combination nanomedicines. A facile one-step ion exchange reaction is utilized to combine a chemotherapeutic (phosphonium) cation and photodynamic therapeutic (porphyrin) anion. An aqueous nanomedicine is prepared from the hydrophobic ionic combination drug via a single-step reprecipitation method. Upon conversion to ionic combination drug, improved photophysical properties of porphyrin were observed. These characteristics subsequently led to increased photodynamic therapeutic activity of nanomedicines—explained by greater singlet oxygen quantum yield. …
Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi
Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi
Arkansas Women in STEM Conference
Herein, we describe a carrier-free combination nanodrug for treatment of cancer. In this work, we combined a photothermal compound and a chemotherapeutic drug using ionic liquid chemistry. We utilized a facile, one-step metathesis approach to replace the counter cation of a near infra-red (NIR) dye (photothermal agent) with a chemotherapeutic cation to synthesize an ionic material-based combination cancer therapy drug to deliver multiple mechanisms simultaneously. The nanodrugs were developed by using a reprecipitation method. The detailed photophysical properties of this new combination therapy molecule was investigated in ethanol solution as well as in nanoparticles forms in aqueous media. The singlet …