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Full-Text Articles in Physical Sciences and Mathematics

Incidence And Cost Of Acute Kidney Injury In Hospitalized Patients With Infective Endocarditis, Victor M. Ortiz-Soriano, Katherine Donaldson, Gaixin Du, Ye Li, Joshua Lambert, Dan Cleland, Alice C. Thornton, Laura C. Fanucchi, Moises A. Huaman, Javier A. Neyra Jun 2019

Incidence And Cost Of Acute Kidney Injury In Hospitalized Patients With Infective Endocarditis, Victor M. Ortiz-Soriano, Katherine Donaldson, Gaixin Du, Ye Li, Joshua Lambert, Dan Cleland, Alice C. Thornton, Laura C. Fanucchi, Moises A. Huaman, Javier A. Neyra

Internal Medicine Faculty Publications

Acute kidney injury (AKI) is a frequent complication of hospitalized patients with infective endocarditis (IE). Further, AKI in the setting of IE is associated with high morbidity and mortality. We aimed to examine the incidence, clinical parameters, and hospital costs associated with AKI in hospitalized patients with IE in an endemic area with an increasing prevalence of opioid use. This retrospective cohort study included 269 patients admitted to a major referral center in Kentucky with a primary diagnosis of IE from January 2013 to December 2015. Of these, 178 (66.2%) patients had AKI by Kidney Disease Improving Global Outcomes (KDIGO) …


Disparities In Prostate Cancer Survival In Appalachian Kentucky: A Population-Based Study, Zin W. Myint, Richard O'Neal, Quan Chen, Bin Huang, Robin C. Vanderpool, Peng Wang May 2019

Disparities In Prostate Cancer Survival In Appalachian Kentucky: A Population-Based Study, Zin W. Myint, Richard O'Neal, Quan Chen, Bin Huang, Robin C. Vanderpool, Peng Wang

Internal Medicine Faculty Publications

Introduction: Prostate cancer (PC) is the most common male cancer in the USA. When comparing the incidence and mortality rates of PC, the Surveillance Epidemiology and End Results data of 2005–2014 show that Appalachian Kentucky had a lower incidence (113/100 000 v 137/100 000) but a higher mortality rate (23.8% v 21.8%) when compared to non-Appalachian Kentucky. The aim of this study was to further characterize the survival disparities of PC between Appalachian and non-Appalachian Kentucky.

Methods: All stages of PC patients diagnosed between 2007 and 2011 were collected through the Kentucky Cancer Registry. Baseline characteristics and survival outcomes were …