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Full-Text Articles in Physical Sciences and Mathematics
Rejoinder Of “Dynamic Treatment Regimes: Technical Challenges And Applications", Eric B. Laber, Daniel J. Lizotte, Min Qian, William Pelham, Susan A. Murphy
Rejoinder Of “Dynamic Treatment Regimes: Technical Challenges And Applications", Eric B. Laber, Daniel J. Lizotte, Min Qian, William Pelham, Susan A. Murphy
Center for Children and Families Faculty Publications
No abstract provided.
Dynamic Treatment Regimes: Technical Challenges And Applications, Eric B. Laber, Daniel J. Lizotte, Min Qian, William E. Pelham, Susan A. Murphy
Dynamic Treatment Regimes: Technical Challenges And Applications, Eric B. Laber, Daniel J. Lizotte, Min Qian, William E. Pelham, Susan A. Murphy
Center for Children and Families Faculty Publications
Dynamic treatment regimes are of growing interest across the clinical sciences because these regimes provide one way to operationalize and thus inform sequential personalized clinical decision making. Formally, a dynamic treatment regime is a sequence of decision rules, one per stage of clinical intervention. Each decision rule maps up-to-date patient information to a recommended treatment. We briefly review a variety of approaches for using data to construct the decision rules. We then review a critical inferential challenge that results from nonregularity, which often arises in this area. In particular, nonregularity arises in inference for parameters in the optimal dynamic treatment …