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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
A Critical Proton Mr Spectroscopy Marker Of Alzheimer Early Neurodegenerative Change: Low Hippocampal Naa/Cr Ratio Impacts Apoe 4 Mexico City Children And Their Parents., Partha S. Mukherjee
A Critical Proton Mr Spectroscopy Marker Of Alzheimer Early Neurodegenerative Change: Low Hippocampal Naa/Cr Ratio Impacts Apoe 4 Mexico City Children And Their Parents., Partha S. Mukherjee
Mathematics Faculty Publications and Presentations
Severe air pollution exposures produce systemic, respiratory, myocardial, and brain inflammation and Alzheimer’s disease (AD) hallmarks in clinically healthy children. We tested whether hippocampal metabolite ratios are associated with contrasting levels of air pollution, APOE and BMI in paired healthy children and one parent sharing the same APOE alleles. We used (1) H-MRS to interrogate bilateral hippocampal single-voxel in 57 children (12.45± 3.4 years) and their 48 parents (37.5± 6.78 years) low pollution city v Mexico City (MC). NAA/Cr, Cho/Cr, and mI/Cr metabolite ratios were analysed. The right hippocampus N-acetylaspartate/creatine (NAA/Cr) was significantly different between cohorts (p=0.007). The NAA/Cr ratio …
Extended Book Review: Really Big Numbers, By Richard Evan Schwartz; The Boy Who Loved Math: The Improbable Life Of Paul Erdös, By Deborah Heiligman; The Short Seller, By Elissa Brent Weissman, Gizem Karaali
Pomona Faculty Publications and Research
The genre of math lit for children is not huge, but it is growing. My kid loves the early reader books by my friend and colleague Julie Glass (A Dollar for Penny (1998), The Fly On the Ceiling (2000)). I found Izolda Fotiyeva’s Math with Mom (2003) too late for my daughter but will definitely read it with my son. For a neat twist on the traditional alphabet book, I recommend The Technical Alphabet (2014) by the engineer sisters Lavanya and Melissa Jawaharlal. More recently a colleague introduced me to Laura Overdeck’s Bedtime Math series; these will soon join …
Mexico City Normal Weight Children Exposed To High Concentrations Of Ambient Pm2.5 Show High Blood Leptin And Endothelin-1, Vitamin D Deficiency, And Food Reward Hormone Dysregulation Versus Low Pollution Controls. Relevance For Obesity And Alzheimer Disease, Partha S. Mukherjee
Mathematics Faculty Publications and Presentations
Millions of Mexico, US and across the world children are overweight and obese. Exposure to fossil-fuel combustion sources increases the risk for obesity and diabetes, while long-term exposure to fine particulate matter (PM 2.5) and ozone (O3) above US EPA standards is associated with increased risk of Alzheimer’s disease (AD). Mexico City Metropolitan Area children are chronically exposed to PM2.5 and O3 concentrations above the standards and exhibit systemic, brain and intrathecal inflammation, cognitive deficits, and Alzheimer disease neuropathology. We investigated adipokines, food reward hormones, endothelial dysfunction, vitamin D and apolipoprotein E (APOE) relationships in …