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Articles 1 - 5 of 5
Full-Text Articles in Physical Sciences and Mathematics
Investigating The Accumulation, Sub-Organ Distribution, And Biochemical Effects Of Nanomaterials Using Mass Spectrometry, Kristen Nicole Sikora
Investigating The Accumulation, Sub-Organ Distribution, And Biochemical Effects Of Nanomaterials Using Mass Spectrometry, Kristen Nicole Sikora
Doctoral Dissertations
Gold nanoparticles (AuNPs) are attractive materials for use in various biomedical applications, such as therapeutic delivery, due to their unique chemical properties and modular tunability. Mass spectrometry methods, including laser desorption/ionization mass spectrometry (LDI-MS) and inductively coupled plasma mass spectrometry (ICP-MS) have been successfully used to evaluate the distribution of AuNPs in complex biological systems. As new AuNP-based materials are developed for applications in therapeutic delivery, it is essential to simultaneously develop analytical techniques that can comprehensively assess their behavior in vivo. In this dissertation, novel mass spectrometric methods have been developed and utilized to evaluate the uptake, distribution, …
Low-Load Metal-Assisted Catalytic Etching Produces Scalable Porosity In Si Powders, Konstantin Tamarov, Riku Kiviluoto, Josph D. Swanson, Bret A. Unger, Alexis T. Ernst, Mark Aindow, Joakim Riikonen, Vesa-Pekka Lehto, Kurt W. Kolasinski
Low-Load Metal-Assisted Catalytic Etching Produces Scalable Porosity In Si Powders, Konstantin Tamarov, Riku Kiviluoto, Josph D. Swanson, Bret A. Unger, Alexis T. Ernst, Mark Aindow, Joakim Riikonen, Vesa-Pekka Lehto, Kurt W. Kolasinski
Chemistry Faculty Publications
The recently discovered low-load metal-assisted catalytic etching (LL-MACE) creates nanostructured Si with controllable and variable characteristics that distinguish this technique from the conventional high-load variant. LL-MACE employs 150 times less metal catalyst and produces porous Si instead of Si nanowires. In this work, we demonstrate that some of the features of LL-MACE cannot be explained by the present understanding of MACE. With mechanistic insight derived from extensive experimentation, it is demonstrated that (1) the method allows the use of not only Ag, Pd, Pt, and Au as metal catalysts but also Cu and (2) judicious combinations of process parameters such …
Chemical Manipulation Of Macrophages: Nanomaterial And Molecular Approaches, Joseph Hardie
Chemical Manipulation Of Macrophages: Nanomaterial And Molecular Approaches, Joseph Hardie
Doctoral Dissertations
Macrophages, phagocytic cells of the innate immune system, are the body’s first line of defense against pathogens and are responsible for tissue maintenance. Macrophages are capable of sensing and internalizing external stimuli, and in response change their morphology and phenotype accordingly. Because macrophages are integral to immune function and tissue maintenance, dysregulation of macrophage behavior is associated with a range of diseases including infections, cancer, autoimmune disorders, atherosclerosis, and more. Because of the implications of macrophage failure, there is interest in creating new materials to manipulate macrophage behavior for a therapeutic effect. In this thesis, I describe the application of …
Enhancing Upconversion Nanoparticle Performance Of Nayf4: Yb,Tm With Doping Optimization And Shell Addition And Of Nayf4: Yb,Er With Yb,Nd Shell Addition, Ashleigh M. Chov
Enhancing Upconversion Nanoparticle Performance Of Nayf4: Yb,Tm With Doping Optimization And Shell Addition And Of Nayf4: Yb,Er With Yb,Nd Shell Addition, Ashleigh M. Chov
Honors Thesis
Upconversion (UC), is a phenomenon that occurs when low-energy excitation (usually near-infrared (NIR)) results in higher-energy emission. Upconversion nanoparticles (UCNPs) are particles less than 100 nm in size that are synthesized using rare earth metals such as Yb, Er, Tm, and Y. UCNPs have important applications in a variety of fields, including bio-imaging, security printing, and latent fingerprint development. Traditional methods for latent fingerprint development such as fluorescent powder dusting have several drawbacks including low contrast, high background interference, and autofluorescence. NIR-to-NIR UCNPs are composed of NaYF4: Yb, Tm and emit 800 nm light under 980 nm excitation …
Powering Advances In Next-Generation Photovoltaics Through Materials Synthesis And Characterization, Christie L.C. Ellis
Powering Advances In Next-Generation Photovoltaics Through Materials Synthesis And Characterization, Christie L.C. Ellis
Doctoral Dissertations
Solar energy is our most abundant natural resource: the energy from sunlight that strikes the Earth in one hour is more than the energy consumed globally in a year. This makes photovoltaics, which convert solar energy into electrical energy, a critical technology to pursue. 95% of the photovoltaic market is dominated by silicon; its high efficiency, stability, and plummeting manufacturing costs made it the clear choice for commercialization. However, silicon solar cells are thick, heavy, opaque, and rigid, limiting potential applications. They are energy- and resource-intensive to produce, and their manufacturing process uses and produces several toxic substances. “Next-generation” photovoltaic …