Physical Sciences and Mathematics Commons^™

Joint Outcome Modeling Using Shared Frailties With Application To Temporal Streamflow Data, Lihua Li

Electronic Thesis and Dissertation Repository

Recently there has been tremendous interest in the development of tools for joint analysis of longitudinal data and time-to-event data. This has gained emphasis particularly in clinical studies, where longitudinal measurements on a response may be recorded along with a time-to-event outcome. Joint analysis of multiple outcomes beyond longitudinal and survival have also been considered, for example, joint analysis of a variety of generalized linear models including continuous and count data, or continuous and binomial data. With joint analysis of multiple outcomes, the interest may be analysis of one outcome conditional on the others, or, more typically, analysis of all …