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Full-Text Articles in Physical Sciences and Mathematics

Data Assimilation For Conductance-Based Neuronal Models, Matthew Moye May 2020

Data Assimilation For Conductance-Based Neuronal Models, Matthew Moye

Dissertations

This dissertation illustrates the use of data assimilation algorithms to estimate unobserved variables and unknown parameters of conductance-based neuronal models. Modern data assimilation (DA) techniques are widely used in climate science and weather prediction, but have only recently begun to be applied in neuroscience. The two main classes of DA techniques are sequential methods and variational methods. Throughout this work, twin experiments, where the data is synthetically generated from output of the model, are used to validate use of these techniques for conductance-based models observing only the voltage trace. In Chapter 1, these techniques are described in detail and the …


Oscillations Via Excitable Cells, Derek Orr, Bard Ermentrout May 2020

Oscillations Via Excitable Cells, Derek Orr, Bard Ermentrout

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Of Pmv Neuronal Circuitry In Adaptive Changes Of Energy Balance, Pilhwa Lee, Cristina Saenz De Miera, Nicole Bellefontaine, Kevin W. Williams, Renata Frazao, Carol Elias May 2020

Modeling Of Pmv Neuronal Circuitry In Adaptive Changes Of Energy Balance, Pilhwa Lee, Cristina Saenz De Miera, Nicole Bellefontaine, Kevin W. Williams, Renata Frazao, Carol Elias

Biology and Medicine Through Mathematics Conference

No abstract provided.


Geometry-Based Estimates Of Glutamate Transporter Density In Astrocytes, Anca R. Radulescu, Cassandra Williams, Annalisa Scimemi May 2020

Geometry-Based Estimates Of Glutamate Transporter Density In Astrocytes, Anca R. Radulescu, Cassandra Williams, Annalisa Scimemi

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref Jan 2020

Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref

Dissertations and Theses

In dynamic environments, split-second sensorimotor decisions must be prioritized according to potential payoffs to maximize overall rewards. The impact of relative value on deliberative perceptual judgments has been examined extensively, but relatively little is known about value-biasing mechanisms in the common situation where physical evidence is strong but the time to act is severely limited. This research examines the behavioral and electrophysiological indices of how value biases split-second perceptual decisions and the possible mechanisms underlying the process. In prominent decision models, a noisy but statistically stationary representation of sensory evidence is integrated over time to an action-triggering bound, and value-biases …