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Full-Text Articles in Physical Sciences and Mathematics

Visualizing Phytochemical-Protein Interaction Networks: Momordica Charantia And Cancer, Yumi L. Briones, Alexander T. Young, Fabian M. Dayrit, Armando Jerome De Jesus, Nina Rosario L. Rojas Dec 2021

Visualizing Phytochemical-Protein Interaction Networks: Momordica Charantia And Cancer, Yumi L. Briones, Alexander T. Young, Fabian M. Dayrit, Armando Jerome De Jesus, Nina Rosario L. Rojas

Chemistry Faculty Publications

The in silico study of medicinal plants is a rapidly growing field. Techniques such as reverse screening and network pharmacology are used to study the complex cellular action of medicinal plants against disease. However, it is difficult to produce a meaningful visualization of phytochemical-protein interactions (PCPIs) in the cell. This study introduces a novel workflow combining various tools to visualize a PCPI network for a medicinal plant against a disease. The five steps are 1) phytochemical compilation, 2) reverse screening, 3) network building, 4) network visualization, and 5) evaluation. The output is a PCPI network that encodes multiple dimensions of …


Comparative Toxicity, Phytochemistry, And Use Of 53 Philippine Medicinal Plants, Lydia M. Clemen-Pascual, Rene Angelo S. Macahig, Nina Rosario L. Rojas Dec 2021

Comparative Toxicity, Phytochemistry, And Use Of 53 Philippine Medicinal Plants, Lydia M. Clemen-Pascual, Rene Angelo S. Macahig, Nina Rosario L. Rojas

Chemistry Faculty Publications

The study compares the toxicity of 53 selected medicinal plants commonly used in the Philippines to treat various diseases. It uses as a benchmark Vitex negundo L., which was approved by the Philippine Food and Drug Administration as an herbal drug for cough and asthma after passing clinical trials for safety and efficacy. The methods were chosen for their simplicity and accessibility even for resource-limited laboratories. Extracts (95 % ethanol) of the medicinal parts of the plants were (1) chemically profiled using qualitative phytochemical tests that detect the presence of key classes of bioactive compounds; and (2) evaluated for toxicity …


A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors Dec 2021

A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors

Biology Faculty Publications

Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind those in the terrestrial and marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five research areas, in an effort to support informed stewardship of freshwater biodiversity. The proposed agenda aims to advance freshwater biodiversity research globally as a critical step in improving coordinated actions towards its sustainable management and conservation.


Classifying Mosquito Presence And Genera Using Median And Interquartile Values From 26-Filter Wingbeat Acoustic Properties, Hernan S. Alar, Proceso L. Fernandez Jr Nov 2021

Classifying Mosquito Presence And Genera Using Median And Interquartile Values From 26-Filter Wingbeat Acoustic Properties, Hernan S. Alar, Proceso L. Fernandez Jr

Department of Information Systems & Computer Science Faculty Publications

Mosquitoes are known to be one of the deadliest creatures in the world. There have been several studies that aim to identify mosquito presence and species using various techniques. The most common ones involve automatic identification of mosquito species from the sounds produced by flapping its wings. The development of these important concepts and technologies can help reduce the spread of mosquito-borne diseases. This paper presents a simple model based on mean and interquartile values that aim to solve the mosquito classification. Despite its simplicity, the proposed model significantly outperforms a Convolutional Neural Network (CNN) model in identifying the mosquito …


Implications Of Covid-19 On Progress In The Un Conventions On Biodiversity And Climate Change, Andrea Monica D. Ortiz, Alaya M. De Leon, Justine Nicole V. Torres, Cecilia Therese T. Guiao, Antonio Gabriel M. La Viña Feb 2021

Implications Of Covid-19 On Progress In The Un Conventions On Biodiversity And Climate Change, Andrea Monica D. Ortiz, Alaya M. De Leon, Justine Nicole V. Torres, Cecilia Therese T. Guiao, Antonio Gabriel M. La Viña

Environmental Science Faculty Publications

2020 was to be a landmark year for setting targets to stop biodiversity loss and prevent dangerous climate change. However, COVID-19 has caused delays to the 15th Conference of the Parties (COP) of the UN Convention on Biological Diversity and the 26th COP of the UN Framework Convention on Climate Change. Negotiations on the Global Biodiversity Framework and the second submission of Nationally Determined Contributions under the Paris Agreement were due to take place at these COPs. There is uncertainty as to how the COVID-19 disruption will affect the negotiations, whether parties will pursue more ambitious actions or take a …


Software And Data Visualization Platform For Groundwater Level And Quality Monitoring System, Carlos M. Oppus, Ma. Aileen Leah G. Guzman, Maria Leonora C. Guico, Jose Claro N. Monje, Mark Glenn F. Retirado, John Chris T. Kwong, Genevieve C. Ngo, Annael J. Domingo Jan 2021

Software And Data Visualization Platform For Groundwater Level And Quality Monitoring System, Carlos M. Oppus, Ma. Aileen Leah G. Guzman, Maria Leonora C. Guico, Jose Claro N. Monje, Mark Glenn F. Retirado, John Chris T. Kwong, Genevieve C. Ngo, Annael J. Domingo

Electronics, Computer, and Communications Engineering Faculty Publications

Rapid urbanization and increasing population come with the increased extraction and use of groundwater resources. To track the effect of these activities on groundwater level and quantity; a system for real-time monitoring is devised. In this paper; we present a software system design that enables a locally-developed groundwater level and water quality monitoring hardware setup to gather water quality parameter data; send it to a cloud server; and present organized data for better visualization. The hardware setup consists of an Arduino microcontroller. Upon deployment; the hardware setup is linked to an Android application that connects to the web-based platform.


Changes In The Philippine Coastal Environment, Karl H. Szekielda, Ma. Aileen Leah G. Guzman Jan 2021

Changes In The Philippine Coastal Environment, Karl H. Szekielda, Ma. Aileen Leah G. Guzman

Environmental Science Faculty Publications

Global warming is progressing at a faster speed than has been estimated earlier in climate forecasting, and the ocean responds rather quickly to global temperature increase. This study uses remotely sensed data that were accessed from the System for Multidisciplinary Research and Applications (NASA Giovanni) to study environmental change in the Philippines’ coast. Monthly averaged sea surface temperature series from around the Philippines indicate that the Philippines follow the global trend in ocean temperature increase and show the increase of about 0.50C within two decades. Despite the high variability in temperature, the linear regressions displayed for all seasons show an …