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Articles 1 - 30 of 50
Full-Text Articles in Physical Sciences and Mathematics
Synthesis, Molecular Characteristics, And Antibacterial Assessment Of Marine Hydroid Aqueous Extract-Based Silver Bio-Nanoparticles, Fredryk Mandey, Aulia Rhamdani Arfan, Rugaiyah Andi Arfah
Synthesis, Molecular Characteristics, And Antibacterial Assessment Of Marine Hydroid Aqueous Extract-Based Silver Bio-Nanoparticles, Fredryk Mandey, Aulia Rhamdani Arfan, Rugaiyah Andi Arfah
Makara Journal of Science
This investigation aims to synthesize, analyze the molecularity, and test the ability of bacterial inhibition capability of silver nanoparticles that have been synthesized by simply mixing silver nitrate and aqueous extracts of marine natural products with and without the addition of amylum as a stabilizing agent. This research, with and without the addition of amylum as a stabilizing agent, obtained 39.0 and 55.2 mg of solids of round-shaped morphology silver nanoparticles with diameters of 87.9 and 103.0 nm., respectively. In addition, the antibacterial testing assay against Staphylococcus aureus and Escherichia coli showed some considerably good results. S. aureus with the …
In Silico Analysis Of C-Type Lectins As Co-Infection Receptors Of Dengue And Chikungunya Viruses In Aedes Aegypti, Munawir Sazali, R. C. Hidayat Soesilohadi, Nastiti Wijayanti, Tri Wibawa, Arif Nur Muhammad Ansori
In Silico Analysis Of C-Type Lectins As Co-Infection Receptors Of Dengue And Chikungunya Viruses In Aedes Aegypti, Munawir Sazali, R. C. Hidayat Soesilohadi, Nastiti Wijayanti, Tri Wibawa, Arif Nur Muhammad Ansori
Makara Journal of Science
Aedes aegypti is a primer vector of dengue virus (DENV) and chikungunya virus (CHIKV). The susceptibility of mosquitoes to DENV and CHIKV depends on their recognition receptor of pathogens. C-type lectins (CTLs) are an important mediator of virus infection in A. aegypti. This study aims to identify potential receptors and determine the binding affinity between ligand–receptor interaction, CTLs and virus envelopes (DENV-1, 2, 3, and 4 and CHIKV) interaction based on in silico analysis. Sample sequences were obtained from GenBank (NCBI), and 10 CTLs were acquired from VectorBase. Homology modeling based on a minimum standard of 20% was processed …
An Inkjet-Printed Graphene Oxide–Poly(3,4-Ethylenedioxythiophene) Poly(Styrene Sulfonate) Electrode For Nitrite Detection In Water, Budi Riza Putra, Weni Anindya, Mohamad Rafi, Ika Kartika, Yudi Nugraha Thaha, Aga Ridhova, Wulan Tri Wahyuni
An Inkjet-Printed Graphene Oxide–Poly(3,4-Ethylenedioxythiophene) Poly(Styrene Sulfonate) Electrode For Nitrite Detection In Water, Budi Riza Putra, Weni Anindya, Mohamad Rafi, Ika Kartika, Yudi Nugraha Thaha, Aga Ridhova, Wulan Tri Wahyuni
Makara Journal of Science
In this study, a screen-printed electrode (SPE) for nitrite (NO2−) sensing was fabricated through an inkjet printing technique using a commercial printer machine and preparing an ink composite solution containing graphene oxide (GO) and poly(3,4 ethylenedioxythiophene) poly(styrene sulfonate) (PEDOT:PSS) as conductive materials. The optimum ink materials for SPE fabrication comprised GO and PEDOT:PSS with binders that resemble the viscosity of commercial ink. The surface topography of the fabricated SPE, which was characterized using scanning electron microscopy and atomic force microscopy, showed a smoother surface compared to the commercial screen-printed carbon electrode, with conductive ink materials deposited primarily …
Free-Radical Scavenging Activity And Total Phenolic Compounds Of Red And Green Poinsettia Leaves (Euphorbia Pulcherrima Willd.) From Lombok Island, Handa Muliasari, Baiq Sopiah, Emmy Yuanita, Baiq Nila Sari Ningsih
Free-Radical Scavenging Activity And Total Phenolic Compounds Of Red And Green Poinsettia Leaves (Euphorbia Pulcherrima Willd.) From Lombok Island, Handa Muliasari, Baiq Sopiah, Emmy Yuanita, Baiq Nila Sari Ningsih
Makara Journal of Science
To determine the free-radical scavenging activity and total phenolic content of the ethanol extract of Poinsettia leaves (Euphorbia pulcherrima Willd.) from Lombok Island, we used the 1,1-diphenyl-2-picrylhydrazyl method and expressed the total phenolic content as gallic acid equivalent (GAE) per gram of ethanol extract. The results show the strong antioxidant activity (79.77 ppm) of the ethanol extract of red Poinsettia leaves and the moderate antioxidant activity of green Poinsettia leaves (118.350 ppm). The ethanol extracts of red and green Poinsettia leaves possessed an average of 63.276 ± 0.228 and 22.715 ± 0.090 mg GAE/g extract total phenolic contents, respectively. …
Enzymatic Screening And Genotypic Characterization Of Thermophilic Bacteria From The Hot Springs Of Sarawak, Malaysia, Seng Chiew Toh, Samuel Lihan, Sui Sien Leong, Azizul Hakim Lahuri, Wai Cheong Woon, Wing Woh Ng
Enzymatic Screening And Genotypic Characterization Of Thermophilic Bacteria From The Hot Springs Of Sarawak, Malaysia, Seng Chiew Toh, Samuel Lihan, Sui Sien Leong, Azizul Hakim Lahuri, Wai Cheong Woon, Wing Woh Ng
Makara Journal of Science
Owing to their eccentric thermostable ability, thermophiles are among the most utilized extremophiles in various industries, such as manufacturing, and clinical research. Researchers believe that many unknown thermophiles are yet to be discovered. This study aimed to genotypically characterize the diversity of thermophiles and screen them for the potential production of enzymes in the recreational hot springs located at Northwest Coast of Borneo. Water samples were collected at 45 °C–50 °C from Annah Rais and Panchor hot springs during the sampling period from January 2018 to January 2019. Three samples (water and sediment) were collected twice in a 3-week interval …
Isolation Of Lignin From Sugarcane Bagasse As An Adsorbent For Chromium Ion, Nila Tanyela Berghuis, Nurul Fitri Novianti, Paramita Jaya Ratri
Isolation Of Lignin From Sugarcane Bagasse As An Adsorbent For Chromium Ion, Nila Tanyela Berghuis, Nurul Fitri Novianti, Paramita Jaya Ratri
Makara Journal of Science
The waste generated in metal coating and leather tanning industries contribute to water pollution owing to the use of Cr metal in production processes. The utilization of lignin from natural base materials in the form of bagasse can reduce unwanted waste from production processes and adsorb Cr ion waste. In this study, lignin was successfully isolated from bagasse waste and then carbonized and applied in Cr metal absorption. Lignin and lignin carbon as an absorbent were characterized using Fourier-transform infrared spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The ability of bagasse lignin and carbon lignin to absorb Cr ion waste …
Synthesis Of Copper (Ii) Oxide Nanoparticles Using Vitis Vinifera L. Leaf Ex-Tract And Its Application As A Catalyst In Doebner Reaction, Felie Virgayani Kurniawan, Antonius Herry Cahyana, Rika Tri Yunarti
Synthesis Of Copper (Ii) Oxide Nanoparticles Using Vitis Vinifera L. Leaf Ex-Tract And Its Application As A Catalyst In Doebner Reaction, Felie Virgayani Kurniawan, Antonius Herry Cahyana, Rika Tri Yunarti
Makara Journal of Science
Plant extracts can be used to synthesize nanoparticle because it is efficient, economical, and friendly to the environment. Copper oxide nanoparticles (CuO NPs) were synthesized using an aqueous fraction of Vitis vinifera L leaf extract and Cu(NO3)2 solution as a precursor. This fraction contains secondary metabolites as a reduction agent and stabilizing agents to formed CuO NPs. CuO NPs can be used as a catalyst in a chemical reaction, one of which is the Doebner reaction, which is a simple and efficient reaction of aniline, aromatic aldehydes, and pyruvic acid under reflux conditions to produce derivatives quinoline-4-carboxylic …
Synthesis, Characterization, Antibacterial Activity, And Potential Water Filter Application Of Copper Oxide/Zeolite Composite, Elfa Aida Kamila, Zaenal Abidin, Irma Isnafia Arief, Trivadila Trivadila
Synthesis, Characterization, Antibacterial Activity, And Potential Water Filter Application Of Copper Oxide/Zeolite Composite, Elfa Aida Kamila, Zaenal Abidin, Irma Isnafia Arief, Trivadila Trivadila
Makara Journal of Science
Detection of E. coli bacteria in water samples can indicate the presence of other bacterial contamination in feces. Bacterial contamination can be treated with antibiotics, but excessive use of antibiotics leads to the emergence of multiresistant bacteria. Therefore, alternative antibacterial agents must be explored. Copper ion/zeolite composite has been widely studied as an antibacterial agent. However, the released copper ions accumulate in water and are toxic to humans; this can be prevented by converting copper ions into copper oxides (CuO and Cu2O). In this study, copper oxide/zeolite composite is synthesized and characterized using the heating method, followed by …
Chicken Immune Responses To Vaccination By The Avian Influenza Subtype H5n1 Against Avian Influenza, Ramlah Ramlah, Sri Murtini, Retno Damayanti Soejoedono, Ketut Karuni Nyanakumari Natih, Siti Gusti Ningrum
Chicken Immune Responses To Vaccination By The Avian Influenza Subtype H5n1 Against Avian Influenza, Ramlah Ramlah, Sri Murtini, Retno Damayanti Soejoedono, Ketut Karuni Nyanakumari Natih, Siti Gusti Ningrum
Makara Journal of Science
Avian Influenza (AI) is one of the strategic animal diseases still considered a priority for control by the Indonesian government. This study aimed to examine the immune response of chickens to various types of H5N1 subtype AI vaccines in Indonesia and to determine the correlation of factors influencing the post-vaccination AI antibody response. Serum samples were tested using the hemagglutination inhibition (HI) test with the standard AI antigen subtype H5N1 strain A/Chicken/Barru/BBVM/41-13/2013 (Clade 2.1.3) and strain A/Chicken/Semarang/04141225-07/2014 (Clade 2.3.2). Antibody titer was calculated using the Geometric Mean Titer (GMT). The correlation analyses were performed to assess the correlation of antibody …
Application Of Photoacoustic Imaging For Pneumonia Detection, Caesarany Maqfiroh, Rini Widyaningrum, Ahmad Mujtahid Anas, Mitrayana Mitrayana
Application Of Photoacoustic Imaging For Pneumonia Detection, Caesarany Maqfiroh, Rini Widyaningrum, Ahmad Mujtahid Anas, Mitrayana Mitrayana
Makara Journal of Science
We used photoacoustic imaging (PAI) to visualize and compare acoustic intensity levels in pneumonia-affected and healthy chicken lungs. After histological confirmation of pneumonia, the samples were scanned and subjected to a 532-nm diode laser in a photoacoustic imaging system. The acoustic intensity level of pneumonia-affected tissue was examined and compared with that of healthy lung samples. The optimum laser frequency and duty cycle for imaging the samples were 17 kHz and 30%, respectively. The acoustic intensity levels of pneumonia-affected tissue and healthy lungs were −82.5 ± 1.8 dB and −79.9 ± 1.3 dB, respectively. We found that a simple PAI …
Physicochemical Changes And Role Of Analytical Chemistry In Black Garlic (Allium Sativum L.) Processing, Surjani Wonorahardjo, Dian Puspita Sari, Arini Salsabila, Estiyawati Estiyawati, Dewi Yuliani, Anugrah Ricky Wijaya, Suharti Suharti, Irma Kartika Kusumaningrum, Chariztya Anggita Maharani, Thjiong Angelina Noviyanti
Physicochemical Changes And Role Of Analytical Chemistry In Black Garlic (Allium Sativum L.) Processing, Surjani Wonorahardjo, Dian Puspita Sari, Arini Salsabila, Estiyawati Estiyawati, Dewi Yuliani, Anugrah Ricky Wijaya, Suharti Suharti, Irma Kartika Kusumaningrum, Chariztya Anggita Maharani, Thjiong Angelina Noviyanti
Makara Journal of Science
Black garlic is a traditional spice having potential of herbal medicine; however, continuous heating darkens its color and changes its taste due to chemical processes and new equilibrium in the system. In this study, fresh garlic was processed into black garlic at 60 °C for 24 days. Changes in physical and chemical parameters, such as browning and protein content, reducing sugar content, and antioxidative components were recorded. Protein content was measured by Kjeldahl method, brown color development was analyzed using a color reader, reducing sugar was examined using a dinitro salicylic DNS reagent, and antioxidative activities were studied with a …
The Potency Of Citrus Aurantiifolia Swingle And Sea Salt Solution As A Cleansing Agent For Edible Bird’S Nests, Siti Gusti Ningrum, Adhitya Yoppy Ro Candra, Hana Cipka Pramuda Wardhani
The Potency Of Citrus Aurantiifolia Swingle And Sea Salt Solution As A Cleansing Agent For Edible Bird’S Nests, Siti Gusti Ningrum, Adhitya Yoppy Ro Candra, Hana Cipka Pramuda Wardhani
Makara Journal of Science
The present study aimed to evaluate the potency of Citrus aurantiifolia Swingle and sea salt solution as a promising cleansing agent for edible bird’s nests (EBNs). Ascorbic acid, sodium, and chloride analyses of the C. aurantiifolia Swingle and sea salt solution were conducted using HPLC, ICP-OES, and titrimetry, respectively. The characteristics of physical samples and hydrogen peroxide detection were examined in this study. The reduction activity of the Citrus aurantiifolia Swingle and sea salt solution on the nitrite of 120 white EBNs was studied. This nitrite reduction activity was compared with the available method (standard), drinking water method, 6% C. …
Modification Of Zeolite Made From Coal Fly Ash With Tio2: Effect Of Aging Time On Physical And Optical Properties, Linda Jati Kusumawardani, Ani Iryani, Ennita Lusiana Sinaga
Modification Of Zeolite Made From Coal Fly Ash With Tio2: Effect Of Aging Time On Physical And Optical Properties, Linda Jati Kusumawardani, Ani Iryani, Ennita Lusiana Sinaga
Makara Journal of Science
The high levels of metal oxides, SiO2, and Al2O3 give coal fly ash the potential for development into zeolite. Zeolite was prepared from fly ash by combining alkaline fusion with hydrothermal treatment. Using this method results in a high surface area, high mechanical properties, and high crystallinity of the sample. Zeolite as a product is modified by TiO2. This study was intended to determine the effect of the operating process in zeolite synthesis from coal fly ash on the types and properties of zeolite and the effect of the aging time of TiO …
Diketopiperazine Cyclo-(S-Pro-R-Leu) Produced By Periconia Pseudobyssoides K5 Isolated From Toona Sureni (Meliaceae) And Its Heme Polymerization Inhibition Activity, Azmi Azhari, Desi Harneti, Asri Peni Wulandari, Yeni Mulyani, Sari Purbaya, Aprilia Permata Sari, Galih Bayu Pratama, Unang Supratman, Yoshihito Shiono
Diketopiperazine Cyclo-(S-Pro-R-Leu) Produced By Periconia Pseudobyssoides K5 Isolated From Toona Sureni (Meliaceae) And Its Heme Polymerization Inhibition Activity, Azmi Azhari, Desi Harneti, Asri Peni Wulandari, Yeni Mulyani, Sari Purbaya, Aprilia Permata Sari, Galih Bayu Pratama, Unang Supratman, Yoshihito Shiono
Makara Journal of Science
Fungi endophytes are living microorganisms colonizing inside the internal tissue of a plant and provide ecological benefits for their host. Endophytes provide various metabolites for plant adaptation toward biotic and abiotic stresses and have tremendous pharmacological activities. Toona sureni (T. sureni) (Meliaceae) belongs to the Toona genera and is reported to have antimalarial activity. To determine the compounds produced by the endophytic fungus from this plant, we isolated a compound from Periconia pseudobyssoides (P. pseudobyssoides) K5 endophytes from the stem bark of T. sureni. Diketopiperazine cyclo-(S-Pro-R-Leu), a non-ribosomal peptide, was isolated from brown …
Potential Effect Of Phlorotannins In Brown Algae For Antidiabetic Therapy: Molecular Docking Approach, Melani Sinastri Renagupita, Rahadianto Rahadianto, Efyluk Garianto, Herin Setianingsih
Potential Effect Of Phlorotannins In Brown Algae For Antidiabetic Therapy: Molecular Docking Approach, Melani Sinastri Renagupita, Rahadianto Rahadianto, Efyluk Garianto, Herin Setianingsih
Makara Journal of Science
This study aims to manifest the effect of the active compound phlorotannins in brown algae on decreasing insulin resistance by analyzing the predicted interaction between phlorotannins and protein tyrosine phosphatase 1B (PTP 1B) and estimating the pharmacokinetics and toxicity of the active compound for type 2 diabetes mellitus (DM) therapy. This type of research uses an in silico study to test the effect of using phlorotannins as an active compound in brown algae against PTP 1B inhibition. Starting from preparing materials, i.e., downloading the three-dimensional structure of phlorotannins via PubChem and PTP 1B via RSCB PDB (PDB 1A5Y), molecular docking …
Synthesis And Study Of Anticancer And Antioxidant Activities Of 2-Oxoquinoline Hydrazide Derivatives, Marwa Khalil Mohamed, Ezzeldin Mohamed S. Salem, Ibrahim Ahmed I. Ali
Synthesis And Study Of Anticancer And Antioxidant Activities Of 2-Oxoquinoline Hydrazide Derivatives, Marwa Khalil Mohamed, Ezzeldin Mohamed S. Salem, Ibrahim Ahmed I. Ali
Makara Journal of Science
In this work, hydrazone, thiosemicarbazide, diamide, and dipeptide derivatives were prepared from the glycine and β-alanine hydrazide of 4-hydroxy-2-oxoquinoline. The desired derivative resulted from substitution, hydrazinolysis, condensation, and azide coupling reactions. The fabricated derivatives were screened for anticancer characteristics toward human’s colon carcinoma (HCT-116) cell line using the 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide viability assay, while antioxidant property was examined using an in vitro H2O2 scavenging method. The β-alanine hydrazide derivative 3a showed a remarkable IC50 value of 18.8 μg/mL, whereas its corresponding thiosemicarbazide 5b exhibited moderate activeness with an IC50 value of 26.89 μg/mL. Conversely, …
Pva-Sansevieria Trifasciata Fraction Films As Absorbers Of Electromagnetic And Thermal Radiation On Smartphones, Nabiila Rahmani, Gustini Syahbirin, Akhiruddin Maddu, Purwantiningsih Sugita, Auliya Ilmiawati
Pva-Sansevieria Trifasciata Fraction Films As Absorbers Of Electromagnetic And Thermal Radiation On Smartphones, Nabiila Rahmani, Gustini Syahbirin, Akhiruddin Maddu, Purwantiningsih Sugita, Auliya Ilmiawati
Makara Journal of Science
Technological developments have prompted the production of highly advanced smartphones. However, various advanced features cause smartphones to heat up quickly and emit more electromagnetic radiation, which harms human health. Smartphone protection is needed to solve these issues. This study aims to create a film from the S. trifasciata plant based on polyvinyl alcohol (PVA) to reduce electromagnetic and thermal radiation on smartphones. S. trifasciata plants were macerated with acetone and partitioned with n-hexane, dichloromethane, ethyl acetate, and water. The films were made by mixing PVA with the four fractions. Among the four layers of film, the PVA + water …
Prevalence And Plasmid Profiles Of Enterobacteriaceae Isolates Obtained From Individuals With Asymptomatic Bacteriuria In Okada, Edo State, Nigeria, Osarumwense Precious Otote, Maureen Uchechukwu Okwu, Osazee Ekundayo Izevbuwa, Happy Ovuerhi Oferiofe
Prevalence And Plasmid Profiles Of Enterobacteriaceae Isolates Obtained From Individuals With Asymptomatic Bacteriuria In Okada, Edo State, Nigeria, Osarumwense Precious Otote, Maureen Uchechukwu Okwu, Osazee Ekundayo Izevbuwa, Happy Ovuerhi Oferiofe
Makara Journal of Science
Asymptomatic bacteriuria (ASB) is the presence of bacteria in apparently healthy individuals. Although, the prevalence varies widely with age, gender, and the presence or absence of genitourinary abnormalities, the detection of pathogenic bacteria in urine constitutes firm evidence of infection. The objectives of this study were to isolate members of the family Enterobacteriaceae from urine samples of research participants, and to determine the antibacterial susceptibility and plasmid profiles of the isolates. A total of 122 mid-stream urine samples consisting of 72 male and 50 female participants from selected primary and secondary schools were collected. The age of the participants used …
Chitosan Oligosaccharides As A Nanomaterial Platform: Biological Properties And Applications In The Biomedical And Pharmaceutical Fields, Muhamad Alif Razi
Chitosan Oligosaccharides As A Nanomaterial Platform: Biological Properties And Applications In The Biomedical And Pharmaceutical Fields, Muhamad Alif Razi
Makara Journal of Science
Chitosan oligosaccharides (COS) have been introduced as marine-derived biomaterials with potential health benefits and good water solubility properties. This study presents an overview of the promising nanomaterial platform for biomedical and pharmaceutical applications of COS. The health benefits of COS, primarily their antioxidant and protective effects, anti-inflammatory activity, antidiabetic properties, and cholesterol-lowering effects are discussed. Furthermore, the promising recent articles on specific topics such as drug delivery systems and nanobiomaterials, are highlighted
Application Of Accuracy And Precision Evaluations Based On The Current United States And Indonesian Pharmacopoeias: A Critical Review, Gunawan Indrayanto
Application Of Accuracy And Precision Evaluations Based On The Current United States And Indonesian Pharmacopoeias: A Critical Review, Gunawan Indrayanto
Makara Journal of Science
New methods for the evaluation of accuracy and precision are mentioned in the latest edition of the United States Pharmacopoeia (USP), whereas other validation parameters, that is, selectivity, linearity, range, and robustness, remained relatively unchanged. In obtaining reliable data from any chemical/pharmaceutical analysis, the analytical procedure must be validated or verified in accordance with the latest edition of the pharmacopoeia. Some review articles on the general validation methods have been published by the author. This present review will focus on the implementation and discussion of the accuracy and precision evaluation based on the current USP and Indonesian pharmacopoeia. Some examples …
Estimation Of The Bubble Point Pressure Of Multicomponent Reservoir Hydrocarbon Fluids, Benjamin Sunday Usen, Chidi Obi
Estimation Of The Bubble Point Pressure Of Multicomponent Reservoir Hydrocarbon Fluids, Benjamin Sunday Usen, Chidi Obi
Makara Journal of Science
This study developed a novel C-sharp (C#) programming language for the estimation of bubble point pressure (BPP) of various hydrocarbon mixtures at equilibrium state. The methodology was based on vapor–liquid equilibrium calculation using Peng Robinson equation of state implementation, thermodynamic equilibrium calculation and Newton-Raphson’s method for the successive substitution of the unknown variables. The equal fugacity constraint can be satisfied by obtaining the equilibrium which serves as a criterion for two or more phases to exist at equilibrium. The problem was resolved by searching for a pressure that will satisfy the two constraints. Complex calculation was performed by successively substituting …
Comparative Photovoltaics Of P3ht:N2200 And P3ht: Small-Gap Fullerene Ethyl-Nipecotate Bulk Heterojunction Structures, Md. Nasir Uddin, Rafiqul Islam, Muhibur Rahman, Nazia Chawdhury
Comparative Photovoltaics Of P3ht:N2200 And P3ht: Small-Gap Fullerene Ethyl-Nipecotate Bulk Heterojunction Structures, Md. Nasir Uddin, Rafiqul Islam, Muhibur Rahman, Nazia Chawdhury
Makara Journal of Science
This work deals with the study on the optical absorption and photoluminescence spectra of a p-type organic semiconducting polymer, regioregular poly 3-hexylthiophene-2,5-diyl (P3HT) and the absorption spectra of an n-type fullerene-based small-gap fullerene-ethyl nipecotate (Fullerene-EN) and a non-fullerene-based polynaphthalene bithiophene (N2200) semiconducting materials. The band gap of P3HT, N2200, and small-gap fullerene-ethyl nipecotate are 2.42, 1.65, and 1.51 eV, respectively, calculated from experimental results through the Tauc equation. Active layers with blends of P3HT and small-gap fullerene-ethyl nipecotate and P3HT and N2200 have been used to fabricate bulk heterojunction (BHJ) structures. The P3HT:N2200 BHJ structure follows the current density versus …
Jatropha Tanjorensis A Flora Of Southeast Nigeria: Isolation And Characterization Of Naringenin And Validation Of Bio-Enhanced Synergistical Activity Of Α- Tocopherol Toward Clinical Isolates Of Resistant Bacterial, Ikechukwu Kingsley Ijoma, Vincent Ishmael Egbulefu Ajiwe
Jatropha Tanjorensis A Flora Of Southeast Nigeria: Isolation And Characterization Of Naringenin And Validation Of Bio-Enhanced Synergistical Activity Of Α- Tocopherol Toward Clinical Isolates Of Resistant Bacterial, Ikechukwu Kingsley Ijoma, Vincent Ishmael Egbulefu Ajiwe
Makara Journal of Science
Jatropha tanjorensis is among the rich floras of Southeast Nigeria and used by ethnic people to treat infections and manage health conditions. Ethnomedicine has long been employed in the treatment of ailments caused by bacterial pathogens. Studies showed that the incorporation of synthetic α-tocopherol to an antibacterial agent improves its activity. However, knowledge about the antibacterial-enhanced activity of plant-based α-tocopherols, especially those isolated from Jatropha tanjorensis, is limited because of the different bioactivities of synthetic and natural α-tocopherols. To determine the phytochemicals in J. tanjorensis, we carried out the structural elucidation of its leaf extracts. Naringenin and α-tocopherol …
Phytochemical, Antibacterial, Antifungal, And Hemagglutination Screening Of Quercus Agrifolia Nee Root Extracts, Abdul Wahab, Arshad Farid, Muhammad Muzammal
Phytochemical, Antibacterial, Antifungal, And Hemagglutination Screening Of Quercus Agrifolia Nee Root Extracts, Abdul Wahab, Arshad Farid, Muhammad Muzammal
Makara Journal of Science
In the current study, the roots of Quercus agrifolia Nee were subjected to phytochemical analysis to determine the presence of various compound groups. To explore the effect of Quercus agrifolia Nee roots, we evaluated four solvent extracts, namely, crude ethanolic extract (CEE), n-hexane, chloroform (CHCl3), and ethyl acetate (EtOAc), for their antibacterial, antifungal, and hemagglutination activities. Agar well diffusion and agar tube dilution methods were used to determine the antibacterial and antifungal effects, respectively, and hemagglutination activity was measured against human erythrocyte blood groups. The qualitative phytochemical analysis of the solvent extracts of Quercus agrifolia Nee roots …
Co-Microencapsulation Of Ruellia Tuberosa L. And Cosmos Caudatus K. Extracts For Pharmaceutical Applications, Choirin Annisa, Sasangka Prasetyawan, Anna Safitri
Co-Microencapsulation Of Ruellia Tuberosa L. And Cosmos Caudatus K. Extracts For Pharmaceutical Applications, Choirin Annisa, Sasangka Prasetyawan, Anna Safitri
Makara Journal of Science
This study aims to co-microencapsulate the Ruellia tuberosa L. and Cosmos caudatus K. extracts, with chitosan–sodium tripolyphosphate (Na-TPP) as coating material. α-Amylase inhibition and antioxidant assays were conducted to determine the potential of microcapsules used as antidiabetic agents. The microcapsules were manufactured under the influences of pH, Na-TPP concentration, and stirring time. The optimum microencapsulation conditions were selected based on the highest encapsulation efficiency. The optimum microencapsulation conditions were a pH of 4, Na-TPP concentration of 0.15% (w/v), and stirring time of 60 min. The microcapsules exhibited an IC50 (inhibitory concentration) value of 223.64 ± 0.81 µg/mL and an …
Silver Nanoparticles’ Biosynthesis And Characterization With The Extract Of Jatropha Curcas Leaf: Analysis Of Corrosion Inhibition Activity, Talabi Henry Kayode, Talabi Justina Yetunde, Adewuyi Benjamin Omotayo
Silver Nanoparticles’ Biosynthesis And Characterization With The Extract Of Jatropha Curcas Leaf: Analysis Of Corrosion Inhibition Activity, Talabi Henry Kayode, Talabi Justina Yetunde, Adewuyi Benjamin Omotayo
Makara Journal of Science
The plant-mediated nanoparticles synthesis process is gaining popularity because of its effective cost, eco-friendliness, and nontoxic nature. The current study presents the silver nanoparticles (AgNPs) which synthesized with AgNO3 as precursor salt and Jatropha curcas leaf extract. J. curcas leaf extract has phytochemicals that could reduce the precursor metal salt to nanoparticles and act as a capping agent surround the nanoparticles to enhance its stability. Phytochemical screening on J. curcas leaf extract showed that alkaloids, saponins, tannins, flavanoids, steroids, philobatannins, phenols, and cardiac glycosides are contained in the sample. The biosynthesized nanoparticles were investigated by UV-visible (UV-vis) spectroscopy, X-ray …
Application Of A Photoacoustic Tomography System: A Case Study On The Monitoring Of Pig Tissue Decomposition, Lusiana Sandra Oey, Mitrayana Mitrayana, Moh. Ali Joko Wasono
Application Of A Photoacoustic Tomography System: A Case Study On The Monitoring Of Pig Tissue Decomposition, Lusiana Sandra Oey, Mitrayana Mitrayana, Moh. Ali Joko Wasono
Makara Journal of Science
Pig carcasses have been used in forensic research because they share several similarities to human cadaver, including decomposition. In several studies, the decomposition of pig’s cadaver for a certain time can be used as a model to determine the time of death of a human. This study was conducted to determine the relationship between the days of spoilage of pig tissue and the level of average sound intensity produced by the sample. Then, in this study, pig skeletal muscles were allowed to decay with a variation of 1–5 days. Afterward, these muscles were imaged using diode laser-based photoacoustic tomography. Results …
Application Of Gellan Gum Biopolymer In Biomedical Applications: A Review, Norsyakirah Izzati Hishamuddin, Mohd Hasmizam Razali, Khairul Anuar Mat Amin
Application Of Gellan Gum Biopolymer In Biomedical Applications: A Review, Norsyakirah Izzati Hishamuddin, Mohd Hasmizam Razali, Khairul Anuar Mat Amin
Makara Journal of Science
Gellan gum (GG) has gained considerable attention in the food, chemical, and pharmaceutical industries due to its functional characteristics. It has versatile properties, such as water solubility, easy bio-fabrication, good film/hydrogel-formation, biodegradability, and biocompatibility. These properties render GG a promising material in biomedical applications, specifically in the development of wound dressing materials. In this review, the use of GG biopolymer as a wound dressing material was discussed. Various fillers, such as titanium dioxides, clay, drug, and honey, have been incorporated in GG to produce film, hydrogel, or scaffold materials. The effects of filler on the mechanical performance, physical properties, antibacterial …
Analysis Of Pelvic Bone Of Ovariectomized Rats Using Infrared And Raman Spectroscopies, Nurwentari Dyah Fitriyawardhani, Ariadne Lakshmidevi Juwono, Neng Nenden Mulyaningsih
Analysis Of Pelvic Bone Of Ovariectomized Rats Using Infrared And Raman Spectroscopies, Nurwentari Dyah Fitriyawardhani, Ariadne Lakshmidevi Juwono, Neng Nenden Mulyaningsih
Makara Journal of Science
Osteoporosis is a bone disease that generally occurs in postmenopausal women. Osteoporosis can be studied using an animal model such as rats because rat bone structure is similar to human bone structure. This research aimed to analyze pelvic bones of ovariectomized rats that showed osteoporosis signs for the first time. In this study, 20 Rattus norvegicus were given ovariectomy at 12 weeks of age and were used as an animal model for menopausal women. The rats were euthanized every 2 weeks from 13 to 21 weeks of age. In addition, the pelvic bones of ovariectomized rats will be analyzed using …
Mercury Contamination In Selected Edible Plants And Soil From Artisanal And Small-Scale Gold Mining In Sukabumi Regency, Indonesia, Grace Serepina Saragih, Ely Rahmi Tapriziah, Yunesfi Syofyan, Siti Masitoh, Yohana Sari Hotmatua Pandiangan, Andriantoro Andriantoro
Mercury Contamination In Selected Edible Plants And Soil From Artisanal And Small-Scale Gold Mining In Sukabumi Regency, Indonesia, Grace Serepina Saragih, Ely Rahmi Tapriziah, Yunesfi Syofyan, Siti Masitoh, Yohana Sari Hotmatua Pandiangan, Andriantoro Andriantoro
Makara Journal of Science
Artisanal and small-scale gold mining (ASGM) activities often pollute soil, water, and air, thereby achieving widespread proliferation, and contaminating the surrounding biota including plants. Mercury contamination on agricultural land around ASGM areas has been widely reported. This study aims to determine the total mercury contamination in plants and soil around active ASGM sites in Sukabumi Regency, Indonesia, namely, Waluran, Lengkong, and Ciemas Districts. Total mercury (Hg) content was measured from 27 plant samples (including cassava [Manihot utilisima], rice [Oryza sativa], and papaya [Carica papaya]), 7 rhizosphere soil samples, and 7 non-rhizosphere soil samples. Data …