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Physical Sciences and Mathematics Commons

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Life Sciences

Chemistry Faculty Publications

Series

2022

Articles 1 - 2 of 2

Full-Text Articles in Physical Sciences and Mathematics

Are We Building Back Better?, Fabian M. Dayrit Dec 2022

Are We Building Back Better?, Fabian M. Dayrit

Chemistry Faculty Publications

No abstract provided.


Nucleobase-Modified Nucleosides And Nucleotides: Applications In Biochemistry, Synthetic Biology, And Drug Discovery, Anthony J. Berdis Nov 2022

Nucleobase-Modified Nucleosides And Nucleotides: Applications In Biochemistry, Synthetic Biology, And Drug Discovery, Anthony J. Berdis

Chemistry Faculty Publications

DNA is often referred to as the "molecule of life " since it contains the genetic blueprint for all forms of life on this planet. The core building blocks composing DNA are deoxynucleotides. While the deoxyribose sugar and phosphate group are ubiquitous, it is the composition and spatial arrangement of the four natural nucleobases, adenine (A), cytosine (C), guanine (G), and thymine (T), that provide diversity in the coding information present in DNA. The ability of DNA to function as the genetic blueprint has historically been attributed to the formation of proper hydrogen bonding interactions made between complementary nucleobases. However, …