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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Towards The Development Of Low-Cost And Easily-Deployable Sensing Platforms For Phosphate, Maureen Pontarelli, Thomas Koch
Towards The Development Of Low-Cost And Easily-Deployable Sensing Platforms For Phosphate, Maureen Pontarelli, Thomas Koch
Chemistry & Biochemistry Student Scholarship
Maureen Pontarelli ’20
Major: Chemistry
Thomas Koch '20
Major: Biochemistry
Faculty Mentor: Dr. John Breen, Chemistry and Biochemistry
Exploration Of K2 Mycobacteriophages With Bred, Colby Agostino, Olivia Schmitt
Exploration Of K2 Mycobacteriophages With Bred, Colby Agostino, Olivia Schmitt
Chemistry & Biochemistry Student Scholarship
Colby Agostino ’22
Major: Biochemistry and Computer Science
Olivia Schmitt ’22
Major: Biochemistry
Faculty Mentor: Dr. Kathleen A. Cornely, Chemistry and Biochemistry
ZoeJ and Marcoliusprime are mycobacteriophage capable of infecting tuberculosis causing bacteria via the lytic and lysogenic cycles. The lytic cycle is the form of viral replication that results in cell death. Lysogeny involves phage DNA being integrated with the DNA of the host cell and preserved through binary fission. However, the bacteria causing tuberculosis do not die in the lysogenic phase. This research project will involve creating mutants of ZoeJ and Marcoliusprime that will not contain the genes …
Mycobacteriophage Morphology As A Diagnostic For Cluster Assignment, Ethan Dionne
Mycobacteriophage Morphology As A Diagnostic For Cluster Assignment, Ethan Dionne
Chemistry & Biochemistry Student Scholarship
Major: Biochemistry
Faculty Mentor: Dr. Kathleen A. Cornely, Chemistry and Biochemistry
Phages are viral bodies that infect bacterial hosts, and have shown promising applications as alternatives to antibiotics for the treatment of bacterial infections. This project examines the morphology of siphoviridae mycobacteriophage, which have long, flexible, non-contractile tails as well as the characteristic head, called a capsid. Using electron microscopy photos of sequenced phages, tail length and capsid diameter were measured and compared to further characterize morphological relationships between genetically distinct phages. The data presented has the potential to work as a diagnostic tool to classify unsequenced phages to genetically …