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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Using Mixed Effects Modeling To Quantify Difference Between Patient Groups With Diabetic Foot Ulcers, Rachel French Dec 2017

Using Mixed Effects Modeling To Quantify Difference Between Patient Groups With Diabetic Foot Ulcers, Rachel French

Mahurin Honors College Capstone Experience/Thesis Projects

When diabetes progresses, many patients suffer from chronic foot ulcers. In a study described in Matrix Metalloproteinases and Diabetic Foot Ulcers (Muller et al., 2008), sixteen patients with diabetic foot ulcers were examined throughout a twelve week healing period. During this period, levels of matrix metalloproteinases (MMP-1), their inhibitors (TIMP-1), and the extracellular matrix in a wound area were measured at distinct time intervals for each patient. The ratios of these healing components are vital in determining whether a wound will heal or become chronic and never properly heal. Connecting Local and Global Sensitivities in a Mathematical Model for Wound …


Detection Of Tetracyclines In An Anaerobic Waste Digester Using Solid Phase Extraction And High-Performance Liquid Chromatography Mass Spectrometry, Courtney Cruse Jun 2017

Detection Of Tetracyclines In An Anaerobic Waste Digester Using Solid Phase Extraction And High-Performance Liquid Chromatography Mass Spectrometry, Courtney Cruse

Mahurin Honors College Capstone Experience/Thesis Projects

Antibiotics are introduced to livestock to encourage growth and for the treatment of diseases. These antibiotics are not completely metabolized by swine, and thus these antibiotics are excreted with their waste. This poses a potential risk to human health as these antibiotics, a potential link to antibiotic resistant bacteria, then enter the surface water, ground water, and soil. In collaboration with the US Department of Agriculture (USDA) in Bowling Green, Kentucky, this research is concerned with analyzing the degradation of tetracyclines in swine waste from an anaerobic digester. Waste samples obtained from a digester and swine waste at the USDA …