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University of Texas Rio Grande Valley
School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations
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Full-Text Articles in Physical Sciences and Mathematics
Effects Of Elevated Temperature On 8-Ohdg Expression In The American Oyster (Crassostrea Virginica): Induction Of Oxidative Stress Biomarkers, Cellular Apoptosis, Dna Damage And Γh2ax Signaling Pathways, Md Faizur Rahman, Mohammad Maruf Billah, Richard J. Kline, Md Saydur Rahman
Effects Of Elevated Temperature On 8-Ohdg Expression In The American Oyster (Crassostrea Virginica): Induction Of Oxidative Stress Biomarkers, Cellular Apoptosis, Dna Damage And Γh2ax Signaling Pathways, Md Faizur Rahman, Mohammad Maruf Billah, Richard J. Kline, Md Saydur Rahman
School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations
Global temperature is increasing due to anthropogenic activities and the effects of elevated temperature on DNA lesions are not well documented in marine organisms. The American oyster (Crassostrea virginica, an edible and commercially important marine mollusk) is an ideal shellfish species to study oxidative DNA lesions during heat stress. In this study, we examined the effects of elevated temperatures (24, 28, and 32 °C for one-week exposure) on heat shock protein-70 (HSP70, a biomarker of heat stress), 8-hydroxy-2’-deoxyguanosine (8-OHdG, a biomarker of pro-mutagenic DNA lesion), double-stranded DNA (dsDNA), γ-histone family member X (γH2AX, a molecular biomarker of DNA damage), …