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Articles 1 - 4 of 4
Full-Text Articles in Physical Sciences and Mathematics
Gardening Resources, Center For Urban Resilience
Gardening Resources, Center For Urban Resilience
Module 10: Garden Ecology
No abstract provided.
Birds In The Urban Landscape, Center For Urban Resilience
Birds In The Urban Landscape, Center For Urban Resilience
Module 10: Garden Ecology
No abstract provided.
Thermostability And Excision Activity Of Polymorphic Forms Of Hogg1, Kathryn Mouzakis
Thermostability And Excision Activity Of Polymorphic Forms Of Hogg1, Kathryn Mouzakis
Chemistry and Biochemistry Faculty Works
Objectives: Reactive oxygen species (ROS) oxidize guanine residues in DNA to form 7,8-dihydro-oxo-2′-deoxyguanosine (8oxoG) lesions in the genome. Human 8-oxoguanine glycosylase-1 (hOGG1) recognizes and excises this highly mutagenic species when it is base-paired opposite a cytosine. We sought to characterize biochemically several hOGG1 variants that have been found in cancer tissues and cell lines, reasoning that if these variants have reduced repair capabilities, they could lead to an increased chance of mutagenesis and carcinogenesis. Results: We have over-expressed and purified the R46Q, A85S, R154H, and S232T hOGG1 variants and have investigated their repair efficiency and thermostability. The hOGG1 variants showed …
Green Chemistry In United States Science Policy, Emily Jarvis
Green Chemistry In United States Science Policy, Emily Jarvis
Chemistry and Biochemistry Faculty Works
Although optimizing each of the Twelve Principles of Green Chemistry is necessary for achieving the greenest possible chemistry in the lab, there are additional creative ways to promote green chemistry not encompassed by these. Communicating to society the importance of green chemistry beyond the laboratory is essential. Of course, doing this effectively presents distinct challenges to those encountered when designing chemical syntheses. Here, I discuss several observations from my time working in federal science policy as an American Association for the Advancement of Science/American Chemical Society Congressional Science Fellow in the United States Senate. I suggest a practical science policy …