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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
People Like Me: Providing Relatable And Realistic Role Models For Underrepresented Minorities In Stem To Increase Their Motivation And Likelihood Of Success, Nir Aish, Philip Asare, Elif Eda Miskioglu
People Like Me: Providing Relatable And Realistic Role Models For Underrepresented Minorities In Stem To Increase Their Motivation And Likelihood Of Success, Nir Aish, Philip Asare, Elif Eda Miskioglu
Faculty Conference Papers and Presentations
Despite efforts to increase participation of racial and ethnic minorities (excluding Asians) in science, technology, engineering and mathematics (STEM) in the United States, this group remains underrepresented in these fields. Many efforts to increase minority participation focus on support structures to help this group “get through” the pipeline. However, less attention has been paid to increasing their intrinsic motivation to pursue careers in STEM. Our work is focused on increasing this intrinsic motivation, looking at role models as external influences. Underrepresented minorities are faced with a limited role model pool and in many cases with role models (who we call …
An Investigation Of Atomic Structures Derived From X-Ray Crystallography And Cryo-Electron Microscopy Using Distal Blocks Of Side-Chains, Lin Chen, Jing He, Salim Sazzed, Rayshawn Walker
An Investigation Of Atomic Structures Derived From X-Ray Crystallography And Cryo-Electron Microscopy Using Distal Blocks Of Side-Chains, Lin Chen, Jing He, Salim Sazzed, Rayshawn Walker
Computer Science Faculty Publications
Cryo-electron microscopy (cryo-EM) is a structure determination method for large molecular complexes. As more and more atomic structures are determined using this technique, it is becoming possible to perform statistical characterization of side-chain conformations. Two data sets were involved to characterize block lengths for each of the 18 types of amino acids. One set contains 9131 structures resolved using X-ray crystallography from density maps with better than or equal to 1.5 Å resolutions, and the other contains 237 protein structures derived from cryo-EM density maps with 2-4 Å resolutions. The results show that the normalized probability density function of block …