Physical Sciences and Mathematics Commons^™

Analysis Of Wastewater Samples To Explore Community Substance Use In The United States: Pilot Correlative And Machine Learning Study, Marie A. Severson, Sathaporn Onanong, Alexandra Dolezal, Shannon L. Bartelt-Hunt, Daniel D. Snow, Lisa M. Mcfadden

Nebraska Water Center: Faculty Publications

Background: Substance use disorder and associated deaths have increased in the United States, but methods for detecting and monitoring substance use using rapid and unbiased techniques are lacking. Wastewater-based surveillance is a cost-effective method for monitoring community drug use. However, the examination of the results often focuses on descriptive analysis.

Objective: The objective of this study was to explore community substance use in the United States by analyzing wastewater samples. Geographic differences and commonalities of substance use were explored.

Methods: Wastewater was sampled across the United States (n=12). Selected drugs with misuse potential, prescriptions, and over-the-counter drugs …