Open Access. Powered by Scholars. Published by Universities.®

Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Engineering

Dissertations and Theses

Microfluidics

Articles 1 - 3 of 3

Full-Text Articles in Physical Sciences and Mathematics

Microfluidic Study Of Gravity-Driven Drainage And Coalescence Of Aqueous Two Dimensional Foams, Justin D. Heftel Jan 2019

Microfluidic Study Of Gravity-Driven Drainage And Coalescence Of Aqueous Two Dimensional Foams, Justin D. Heftel

Dissertations and Theses

Foams, a two-phase dispersion, are staples of the cosmetic, personal care, petroleum, pharmaceutical, and other industries. Central to these applications is the stability of the dispersion against separation. Foams break down by two mechanisms: the first is bubble coalescence, which is driven by the gravity drainage of the continuous phase. The drainage acts to push the bubbles against each other, and leads to the formation of thin lamellae, which break and cause the coalescence. The second is the mass transfer of the dispersed phase through the continuous phase, which is caused by the difference in pressures between the bubbles and …


Developing A 3d In Vitro Model By Microfluidics, Hung-Ta Chien Jan 2018

Developing A 3d In Vitro Model By Microfluidics, Hung-Ta Chien

Dissertations and Theses

In vitro tissue models play an important role in providing a platform that mimics the realistic tissue microenvironment for stimulating and characterizing the cellular behavior. In particular, the hydrogel-based 3D in vitro models allow the cells to grow and interact with their surroundings in all directions, thus better mimicking in vivo than their 2D counterparts. The objective of this thesis is to establish a 3D in vitro model that mimics the anatomical and functional complexity of the realistic cancer microenvironment for conveniently studying the transport coupling in porous tissue structures. We pack uniform-sized PEGDA-GelMA microgels in a microfluidic chip to …


Analysis Of Capillary Flow In Interior Corners : Perturbed Power Law Similarity Solutions, Joshua Thomas Mccraney Dec 2015

Analysis Of Capillary Flow In Interior Corners : Perturbed Power Law Similarity Solutions, Joshua Thomas Mccraney

Dissertations and Theses

The design of fluid management systems requires accurate models for fluid transport. In the low gravity environment of space, gravity no longer dominates fluid displacement; instead capillary forces often govern flow. This thesis considers the redistribution of fluid along an interior corner. Following a rapid reduction of gravity, fluid advances along the corner measured by the column length z = L(t), which is governed by a nonlinear partial differential equation with dynamical boundary conditions. Three flow types are examined: capillary rise, spreading drop, and tapered corner. The spreading drop regime is shown to exhibit column length growth L ~ …