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Engineering

Computer Science and Engineering Faculty Publications

Metabolomics

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Full-Text Articles in Physical Sciences and Mathematics

Metabolomics Characterization Of U.S. And Japanese F-15 And C-130 Flight Line Crews Exposed To Jet Fuel Volatile Organic Compounds And Aerosols, Nicholas J. Delraso, David Mattie, Asao Kobayashi, Stephen W. Mitchell, Scott Dillard, Michael L. Raymer, Isaie Sibomana, Nicholas V. Reo Sep 2014

Metabolomics Characterization Of U.S. And Japanese F-15 And C-130 Flight Line Crews Exposed To Jet Fuel Volatile Organic Compounds And Aerosols, Nicholas J. Delraso, David Mattie, Asao Kobayashi, Stephen W. Mitchell, Scott Dillard, Michael L. Raymer, Isaie Sibomana, Nicholas V. Reo

Computer Science and Engineering Faculty Publications

Air and ground crews transfer a significant amount of jet fuel, and as a result of transfers, breathe its volatile emission from residues. Working on the flight line also exposes maintainers to exhaust from the jet fuel as engines are tested or run before and after flight. Since little is known concerning level of exposure and the corresponding biological response associated with human jet fuel exposure, nuclear magnetic resonance (NMR)-based metabolomics analysis of human urine was utilized for characterization of metabolite profiles of flight line personnel for potential biomarker discovery. This project was a collaborative research effort between the US …


Biomarkers Of Fatigue: Metabolomics Profiles Predictive Of Cognitive Performance, Nicholas J. Delraso, Deirdre A. Mahle, John J. Schlager, Donald L. Harville, Scott R. Chaiken, Danelle K. Roddy, Mari Chamberlain, Paul E. Anderson, Nicholas V. Reo, Michael L. Raymer, Isaie Sibomana May 2013

Biomarkers Of Fatigue: Metabolomics Profiles Predictive Of Cognitive Performance, Nicholas J. Delraso, Deirdre A. Mahle, John J. Schlager, Donald L. Harville, Scott R. Chaiken, Danelle K. Roddy, Mari Chamberlain, Paul E. Anderson, Nicholas V. Reo, Michael L. Raymer, Isaie Sibomana

Computer Science and Engineering Faculty Publications

Cognitive performance and fatigue are well known to be inversely related. Continuous and sustained actions in operational environments typically lead to reduced sleep normally required to perform optimally. These operational environments subject the warfighter to intense physical and mental exertion. Because fatigue continues to be an occupational hazard, leading to cognitive defects in performance, there has been a recognized need for real-time detection technologies that minimize fatigue-induced mishaps. I the current study, 23 subjects were subjected to 36h of sleep deprivation and cognitive psychomotor vigilance and automated neuropsychological assessment metric tests were conducted over the last 24 h of sleep …