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Engineering

Nova Southeastern University

Biomarkers

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Full-Text Articles in Physical Sciences and Mathematics

Integrating The Spatial Pyramid Pooling Into 3d Convolutional Neural Networks For Cerebral Microbleeds Detection, Andre Accioly Veira Jan 2023

Integrating The Spatial Pyramid Pooling Into 3d Convolutional Neural Networks For Cerebral Microbleeds Detection, Andre Accioly Veira

CCE Theses and Dissertations

Cerebral microbleeds (CMB) are small foci of chronic blood products in brain tissues that are critical markers for cerebral amyloid angiopathy. CMB increases the risk of symptomatic intracerebral hemorrhage and ischemic stroke. CMB can also cause structural damage to brain tissues resulting in neurologic dysfunction, cognitive impairment, and dementia. Due to the paramagnetic properties of blood degradation products, CMB can be better visualized via susceptibility-weighted imaging (SWI) than magnetic resonance imaging (MRI).CMB identification and classification have been based mainly on human visual identification of SWI features via shape, size, and intensity information. However, manual interpretation can be biased. Visual screening …


Personalized Medicine: The Use Of Biomarkers And Molecularly Targeted Therapies For Patient Care And Cancer Intervention, Wafa Asad, Emily Schmitt Lavin Sep 2020

Personalized Medicine: The Use Of Biomarkers And Molecularly Targeted Therapies For Patient Care And Cancer Intervention, Wafa Asad, Emily Schmitt Lavin

Mako: NSU Undergraduate Student Journal

Personalized medicine and targeted therapy have been emerging fields of study for the remediation and inhibition of cancer. Personalized medicine in the treatment of cancer involves using genetic, immune, and proteomic profiling to provide therapeutic options as well as prognostic background for every patient and their tumor’s genetic mutations. Targeted therapies allow researchers and medical personnel alike to determine the appropriate treatment for a patient based on the molecular basis and mechanistic actions of a cancerous tumor. The overall significance of this study was to express how these treatments use biomarkers to pinpoint the location, and severity of the cancer, …