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Physical Sciences and Mathematics Commons™
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Articles 1 - 4 of 4
Full-Text Articles in Physical Sciences and Mathematics
Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han
Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han
Michigan Tech Publications, Part 2
Within the vascular system, endothelial cells (ECs) are exposed to fluid shear stress (FSS), a mechanical force exerted by blood flow that is critical for regulating cellular tension and maintaining vascular homeostasis. The way ECs react to FSS varies significantly; while high, laminar FSS supports vasodilation and suppresses inflammation, low or disturbed FSS can lead to endothelial dysfunction and increase the risk of cardiovascular diseases. Yet, the adaptation of ECs to dynamically varying FSS remains poorly understood. This study focuses on the dynamic responses of ECs to brief periods of low FSS, examining its impact on endothelial traction-a measure of …
Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish K. Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han
Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish K. Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han
Michigan Tech Publications, Part 2
Within the vascular system, endothelial cells (ECs) are exposed to fluid shear stress (FSS), a mechanical force exerted by blood flow that is critical for regulating cellular tension and maintaining vascular homeostasis. The way ECs react to FSS varies significantly; while high, laminar FSS supports vasodilation and suppresses inflammation, low or disturbed FSS can lead to endothelial dysfunction and increase the risk of cardiovascular diseases. Yet, the adaptation of ECs to dynamically varying FSS remains poorly understood. This study focuses on the dynamic responses of ECs to brief periods of low FSS, examining its impact on endothelial traction—a measure of …
Assessment Of Post-Wildfire Debris Flow Occurrence Using Classifier Tree, Priscilla Addison, Thomas Oommen, Qiuying Sha
Assessment Of Post-Wildfire Debris Flow Occurrence Using Classifier Tree, Priscilla Addison, Thomas Oommen, Qiuying Sha
Michigan Tech Publications
Besides the dangers of an actively burning wildfire, a plethora of other hazardous consequences can occur afterwards. Debris flows are among the most hazardous of these, being known to cause fatalities and extensive damage to infrastructure. Although debris flows are not exclusive to fire affected areas, a wildfire can increase a location’s susceptibility by stripping its protective covers like vegetation and introducing destabilizing factors such as ash filling soil pores to increase runoff potential. Due to the associated dangers, researchers are developing statistical models to isolate susceptible locations. Existing models predominantly employ the logistic regression algorithm; however, previous studies have …
Property Analysis Of Exfoliated Graphite Nanoplatelets Modified Asphalt Model Using Molecular Dynamics (Md) Method, Hui Yao, Qingli Dai, Zhanping You, Andreas Bick, Min Wang, Shuaicheng Guo
Property Analysis Of Exfoliated Graphite Nanoplatelets Modified Asphalt Model Using Molecular Dynamics (Md) Method, Hui Yao, Qingli Dai, Zhanping You, Andreas Bick, Min Wang, Shuaicheng Guo
Michigan Tech Publications
This Molecular Dynamics (MD) simulation paper presents a physical property comparison study between exfoliated graphite nanoplatelets (xGNP) modified and control asphalt models, including density, glass transition temperature, viscosity and thermal conductivity. The three-component control asphalt model consists of asphaltenes, aromatics, and saturates based on previous references. The xGNP asphalt model was built by incorporating an xGNP and control asphalt model and controlling mass ratios to represent the laboratory prepared samples. The Amber Cornell Extension Force Field (ACEFF) was used with assigned molecular electro-static potential (ESP) charge from NWChem analysis. After optimization and ensemble relaxation, the properties of the control and …