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Image-Based Identification Of Cell Cultures By Machine Learning, Oluleye Hezekiah Babatunde
Image-Based Identification Of Cell Cultures By Machine Learning, Oluleye Hezekiah Babatunde
Oluleye Babatunde
Biomedical laboratories often use different cell types in the same assay or the same cell type in different
assays. One cell type can become contaminated by another, or cells can be mis-identified, giving poor
results. Addressing these issues by DNA analyses can be time-consuming, labor intensive or costly to
implement. Here we uniquely employ Legendre moments (LM), Zernike moments (ZM), circularity and
a genetic algorithm (GA) to advance a computer-based vision system, and we task it to identify four cell
types used in virology: HeLa, Vero, BHK and PC3. By employing a k-nearest neighbor (kNN), multilayer
perceptron (MLP), Convolutional Neural …