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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Chemistry

2018

Journal of Electrochemistry

Acetylcholinesterase

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Full-Text Articles in Physical Sciences and Mathematics

Acetylcholinesterase Biosensor Platform Based On Bp2000 For The Detection Of Carbaryl, Ming-Han Zhang, Jun-Qiao Jiang, Jun-Jie Ge, Wei Xing Aug 2018

Acetylcholinesterase Biosensor Platform Based On Bp2000 For The Detection Of Carbaryl, Ming-Han Zhang, Jun-Qiao Jiang, Jun-Jie Ge, Wei Xing

Journal of Electrochemistry

With the purpose of providing a new method for carbaryl (a pesticide) detection, on the basis of the principle that acetylcholinesterase (AChE) activity can be restrained by carbaryl, an AChE biosensor platform based on BP2000 (as a fixation) was constructed by dropping method. As a result, it revealed that AChE immobilized on BP2000 maintained its catalytic activity for acetylcholine (ATCl), and due to the introduction of the BP2000 material, the effective electrochemical surface area of the modified electrode was enlarged. In addition, the electrochemical oxidation at the modified electrode occurred at low potential (0.630 V) accompanied by proton transmission. The …