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Full-Text Articles in Physical Sciences and Mathematics
The Effects Of Structural Modification Of The Wing Helix Domain Of Pria On Bacterial Dna, Erich Auer
The Effects Of Structural Modification Of The Wing Helix Domain Of Pria On Bacterial Dna, Erich Auer
Honors Theses
During a cell’s life it must copy itself or face death. For the cell to form a new copy it must replicate its DNA, this DNA is the blueprint for the essential components of the cell. The replication process does not always go to completion, which is necessary for the cell to survive, so there are mechanisms to keep the replication process running smoothly. In bacteria, PriA is used to restart replication after damage to the DNA. By looking at the structure of PriA we can start to determine how exactly it works with the damaged DNA and restart the …
Preparation, Analysis And Derivatization Of Benzotris(Thiazole) Triamine, Jonathan Patrick Peter Alessi
Preparation, Analysis And Derivatization Of Benzotris(Thiazole) Triamine, Jonathan Patrick Peter Alessi
Honors Theses
Multiple fields are areas of active research where organic materials hold considerable promise, such as thermoelectrics or photovoltaics. In an effort to design and prepare a new system which would exhibit a set of promising features such as high thermal stability, high degree of planarity, rigid skeleton and strong electron accepting properties, we have undertaken the preparation and characterization of benzotrithiazole and its derivatives. Our work has led to a reproducible and scalable protocol for the generation of one particular structure: benzo[1,2-d:3,4-d':5,6-d"]tris(thiazole)-2,5,8-triamine. We have also conducted further attempts to functionalize this structure, leading to other derivatives of the target compound.
Synthesis Of Bis(Quinoxalino) Ligand For The Removal Of Transition Metal Contamination, Alexander J. Farmer
Synthesis Of Bis(Quinoxalino) Ligand For The Removal Of Transition Metal Contamination, Alexander J. Farmer
Honors Theses
Transition metal contamination is a constant concern both in the environment and in chemical reaction mixtures. One proposed solution, is the use of peraza-crown macrocycles to selectively bind and remove transition metals. The aim of our project is to determine the novel synthesis of bis(quinoxalino) peraza-crown macrocycles for use as ligands to bind to transition metals. Our proposed molecules incorporate the rigid quinoxaline subunit into an aza-crown macrocycle which can improve binding properties. The synthesis route is novel and overcomes several limitations of the existing methods of aza-crown macrocycle preparation. We have designed the synthesis in such a way that …