Physical Sciences and Mathematics Commons^™

Hydroxyl Number Determination Of Dendritic Polyols Utilizing Nir Spectroscopy, Seth Stacey

Honors Theses

The goal of this project was to investigate the use of NIR-spectroscopy to quantify the number of OH functional groups attached to poly(amido amine) or PAMAM dendrimers in a manner that is quick, cost effective and easily reproducible. Obtaining the approximate number of hydroxyl functional groups (OH#) in a dendrimer is crucial in determining what role it can play in bonding and reactivity to other molecules. NIR-spectroscopy has the potential to allow for the recovery of the sample or at least to minimize the amount needed for analysis while providing an accurate determination of the OH# of a dendrimer.