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Full-Text Articles in Physical Sciences and Mathematics
Bioactivity Assessment Of Veratrum Californicum Alkaloids, Madison Dirks
Bioactivity Assessment Of Veratrum Californicum Alkaloids, Madison Dirks
Boise State University Theses and Dissertations
The native Idaho plant Veratrum californicum is known to contain steroidal alkaloids that function as inhibitors of hedgehog signaling, a pathway utilized for the growth and differentiation of cells as well as proper tissue development. Veratrum californicum was originally noticed when pregnant ewes consumed the plant and later gave birth to lambs with craniofacial mutations such as a cyclopean eyes. These malformations were caused by the plant’s steroidal alkaloid cyclopamine blocking the hedgehog signaling pathway. This same pathway is used by more than 20 types of cancer for multiplication of cells. Additional alkaloids have been found in Veratrum californicum, …
Exploring Electron-Sink Behaviors Of Molecular Assemblies, Yume Mai
Exploring Electron-Sink Behaviors Of Molecular Assemblies, Yume Mai
Boise State University Theses and Dissertations
Metal carbonyl clusters, such as the [Ni32C6(CO)36]6- anion, have been documented to display electron-sink phenomena. However, such large clusters suffer from inefficient yields due to their demanding and unreliable synthesis routes. To approach this obstacle, we investigated the electrochemical properties of Fe2(μ-PPh2)2(CO)6, an organometallic complex known to experience a reversible two-electron transfer process. In this work, we report a modular synthetic strategy for expanding the electron-sink capacity of molecular assemblies by installing Fe2(μ-PPh2)2(CO)6 redox mediators to arylisocyanide ligands. …
Whey Protein Powder Analysis By Kjeldahl And Mid-Infrared Spectroscopy, Rose Saxton
Whey Protein Powder Analysis By Kjeldahl And Mid-Infrared Spectroscopy, Rose Saxton
Boise State University Theses and Dissertations
There is an ever-expanding number of high protein dietary supplements marketed as beneficial to athletes, body builders, infant formulas, elder care, and animal feed. Consumers will pay more for products with high protein per serving data on their nutritional labels, making the accurate reporting of protein content critical to customer confidence. The Kjeldahl Method (KM) is the industry standard to quantitate dairy proteins, but the result is based on nitrogen content, which is an approximation of nitrogen attributable to protein in milk. Optical spectroscopy is commonly used for quality control measurements and has been identified as having the potential to …
New Applications For The Kinetic Exclusion Assay (Kinexa), Mark Harrison Smith
New Applications For The Kinetic Exclusion Assay (Kinexa), Mark Harrison Smith
Boise State University Theses and Dissertations
This dissertation examines the fundamental principles and applicability of the kinetic exclusion assay (KinExA), developed and marketed by Sapidyne Instruments of Boise, Idaho, since 1995. Chapter One reviews and consolidates the manufacturer’s guidance and many early papers that delineate the practical and theoretical aspects of the technology. In brief, KinExA is a two stage analytical system. In stage one, a number of solutions are prepared, whereby one of the partners is kept constant (the constant binding partner, or CBP), while the other (the titrant) is varied, usually in serial dilution. As the titrant is increased, the free CBP decreases, and …