Physical Sciences and Mathematics Commons^™

Miniaturized Fractionation And Purification Of Analytes Of Interest In Complex Mixtures: Protein Enrichment And Purification With Capillary Electrophoresis And Identification Of Pesticide Chemicals In Bio-Oils, Christina J. Booker

Electronic Thesis and Dissertation Repository

The ability to isolate and detect an analyte of interest is vital for many different facets of life today, from disease detection to environmental safety. The goal of the method development discussed within this thesis is to isolate and identify unique analytes from complex matrices and to do so in a scaled down approach. Removal of an analyte from a diverse background of molecules is often required for successful detection and determination of analyte properties. As well, many samples are only available at low volumes and at trace levels so miniaturized techniques that only require small sample volumes are designed …