Physical Sciences and Mathematics Commons^™

A Selectivity Study On The Use Of Caffeine And Theobromine Imprinted Polypyrrole Surface Electrodes, Anil Kiran Kumar Vinjamuri

Masters Theses & Specialist Projects

Molecularly imprinted polymers (MIPs) are proving to be very effective in development of synthetic recognition systems and are of great interest to those interested in the field of sensor technology. The use of MIPs is receiving considerable interest due to the ability to prepare recognition matrices that possess high substrate selectivity and specificity. Conducting polymers (CP) have proved to be an excellent tool for the preparation of nano-structured biologically selective systems. Polypyrrole (Ppy) is one such CP that is extensively used for the construction of bioanalytical sensors. Ppy has shown great promise primarily due to its biocompatibility and thermal stability …

Admicelle-Based Solid Phase Extraction Of Phenols Using Dialkylammonium Surfactant In The Hydroxide Form, Kali R. Pickering

Masters Theses & Specialist Projects

A technique for admicelle-based solid phase extraction is presented in which a dialkylammonium surfactant in the hydroxide form is immobilized on silica. By converting dihexadecyldimethylammonium bromide to the hydroxide form, the surfactant is allowed to have the property of a strong base, aiding in the extraction of acidic phenols which are difficult to extract because of their differing polarities. The surfactant-silica admicelle parameters were optimized for the efficient extraction of eight phenols. Adsorbed phenols were eluted from the sorbent using small volumes of methanol. The phenols were preconcentrated from drinking water samples and were determined using high performance liquid chromatography …

Proposed Route To Cyclopenta[C]Thiophenes Via Activated Methylene, Vineet V. Karambelkar

Masters Theses & Specialist Projects

The synthesis of cyclopenta[c]thiophenes has been sparsely reported in the literature owing to several difficulties involved in their synthesis. The present work involves the proposed synthesis of cyclopenta[c]thiophenes and their precursors using activated methylene. Cyclopenta[c]thiophene compounds show promise in the field of polymer and catalysis chemistry. These substituted polythiophenes are potential organic semiconductors and anti-tumor agents. The research presented shows the successful and novel conversion of 3,4-bis(chloromethyl)-2,5-dimethylthiophene and 3,4-bis(bromomethyl)-2,5-dimethylthiophene to a fused 5,5'-fused membered ring which is the precursor to cyclopenta[c]thiophene the sulfone ester, 5-carbomethoxy-5- phenylsulfonyl-1,3-dimethyl-5,6-dihydro-4H-cyclopenta[c]thiophene, in just two steps as compared to four steps previously reported in the literature. …

A Study On The Protein Interaction With Different Platinum Compounds, Nayna Kotadia

Masters Theses & Specialist Projects

Since the discovery of anti-tumor activity of cisplatin in 1960, significant progress has been made in treating metastatic or advanced cancer with cisplatin and platinum compounds. Platinum compounds covalently bind to DNA and disrupt DNA function. They are also known to bind with amino acids like methionine, histidine and cysteine to form cisplatin-protein adducts which are responsible for most of its cytotoxicity and side effects. Recent articles on cisplatin-protein have shown that adding bulky adjuncts to cisplatin or using different platinum compounds varies the degree and extent of reaction thus possibly reducing cisplatin resistance and side effects.

One of the …

Optimization Of Microwave-Assisted Acid Digestion Method For Determination Of Trace Elements In Coal And Coal Fly Ash, Dejan Savic

Masters Theses & Specialist Projects

In most of the analytical and environmental laboratories today inductively coupled plasma (ICP) is a method of choice for analysis of trace metal elements present in coal and coal combustion products. This method requires use of liquid samples, so all coal and coal combustion products must be digested prior to analysis by ICP. Traditionally an open-air hot-plate acid digestion method published as ASTM D6357-04 was used to extract all trace metal elements into solution.

Recent development of microwave systems designed for digestions under extreme acidic conditions and high temperatures and pressures shifted focus toward more rapid and precise microwave-assisted digestion …

Chemistry And The Automotive Industry, Jeremy Pedigo

Masters Theses & Specialist Projects

This thesis covers the use of chemistry in the automotive industry with emphasis on environmental compliance via chemical reporting by database and internal Energy Dispersive X-ray Fluorescence (XRF) screening, third party laboratory material testing, and the future of the chemist in the United States (U.S.) automotive industry. The third party testing was performed at Western Kentucky University (WKU) via the Materials Characterization Center (MCC), Institute for Combustion Science and Environmental Technology (ICSET) Thermodynamics Laboratory, and using the Scanning Electron Microscope/Energy Dispersive X-ray Spectrometer (SEM/EDX) managed by the WKU Biotechnology Center. Furthermore, the tests conducted were used to investigate material defects, …

Ua66/1/5 Icset - Institute For Combustion Science & Environmental Technology, Wku Ogden College Of Science & Engineering

WKU Archives Records

History and overview of the work of the WKU Institute for Combustion Science & Environmental Technology through 2008.