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Physical Sciences and Mathematics Commons

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Chemistry

University of Texas Rio Grande Valley

2010

Iodine

Articles 1 - 2 of 2

Full-Text Articles in Physical Sciences and Mathematics

An Effective Microwave-Induced Iodine-Catalyzed Method For The Synthesis Of Quinoxalines Via Condensation Of 12-Diamines With 12-Dicarbonyl Compounds, Debasish Bandyopadhyay, Sanghamitra Mukherjee, Robert R. Rodriguez, Bimal K. Banik Jun 2010

An Effective Microwave-Induced Iodine-Catalyzed Method For The Synthesis Of Quinoxalines Via Condensation Of 12-Diamines With 12-Dicarbonyl Compounds, Debasish Bandyopadhyay, Sanghamitra Mukherjee, Robert R. Rodriguez, Bimal K. Banik

Chemistry Faculty Publications and Presentations

A microwave-induced iodine-catalyzed simple, rapid and convenient synthesis of different types of quinoxalines via condensation of 1,2-diamines with 1,2-dicarbonyl compounds has been accomplished with an excellent yield.


Remarkable Iodine-Catalyzed Synthesis Of Novel Pyrrole- Bearing N-Polyaromatic B-Lactams, Debasish Bandyopadhyay, Gildardo Rivera, Isabel Salinas, Hector Aguilar, Bimal K. Banik Feb 2010

Remarkable Iodine-Catalyzed Synthesis Of Novel Pyrrole- Bearing N-Polyaromatic B-Lactams, Debasish Bandyopadhyay, Gildardo Rivera, Isabel Salinas, Hector Aguilar, Bimal K. Banik

Chemistry Faculty Publications and Presentations

Because of their interesting biological properties various methods for the synthesis of substituted pyrroles are described in the literature. However, synthesis of pyrroles fused with a β-lactam ring has not been reported. Our group has demonstrated synthesis and biological evaluation of various β-lactams as anticancer agents. The anticancer activities of these compounds have prompted us to study the synthesis of pyrroles bound to the β-lactams. We have identified an expeditious synthetic method for the preparation of pyrroles fused with β-lactams by reacting 3-amino β-lactams with acetonylacetone in the presence of catalytic amounts (5 mol%) of molecular iodine at room temperature. …