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Full-Text Articles in Physical Sciences and Mathematics
Synthesis Of Β,Β-Disubstituted Styrenes Via Trimethylsilyl Trifluoromethanesulfonate-Promoted Aldehyde-Aldehyde Aldol Addition-Deformylative Elimination., Grant J. Dixon, Michael R. Rodriguez, Tyler G. Chong, Kevin Y. Kim, C. Wade Downey
Synthesis Of Β,Β-Disubstituted Styrenes Via Trimethylsilyl Trifluoromethanesulfonate-Promoted Aldehyde-Aldehyde Aldol Addition-Deformylative Elimination., Grant J. Dixon, Michael R. Rodriguez, Tyler G. Chong, Kevin Y. Kim, C. Wade Downey
Chemistry Faculty Publications
In the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and 2,6-lutidine, α,α-disubstituted aldehydes condense with electron-rich aromatic aldehydes to yield β, β- disubstituted styrenes. More electron-rich aromatic aldehydes react more rapidly and in higher yield. Preliminary results suggest that the reaction may proceed via the ionization and formal deformylation of an aldol intermediate.
Trimethylsilyl Trifluoromethanesulfonate- Accelerated Addition Of Catalytically Generated Zinc Acetylides To Aldehydes, C. Wade Downey, Brian D. Mahoney, Vincent R. Lipari
Trimethylsilyl Trifluoromethanesulfonate- Accelerated Addition Of Catalytically Generated Zinc Acetylides To Aldehydes, C. Wade Downey, Brian D. Mahoney, Vincent R. Lipari
Chemistry Faculty Publications
In the presence of TMSOTf, a wide variety of terminal acetylenes add rapidly and efficiently to aldehydes via a catalytically generated zinc acetylide. In the absence of TMSOTf, no reaction is observed under otherwise identical conditions.
A Series Of Vertically Integrated Nanotechnology Experiments For The Undergraduate Curriculum, Kevin W. Kittredge, Lesley E. Russell, Michael C. Leopold
A Series Of Vertically Integrated Nanotechnology Experiments For The Undergraduate Curriculum, Kevin W. Kittredge, Lesley E. Russell, Michael C. Leopold
Chemistry Faculty Publications
We have designed three nanotechnology experiments that are vertically integrated for an undergraduate chemistry curriculum. They are an evolving set of experiments for sequential courses in an undergraduate chemistry program. These experiments are designed to match the student's level of understanding for each particular course. The participating student is involved in a "research" project that progresses in both theory and experimental technique. Students benefit from these vertically integrated experiments by being involved in multiple facets of a simulated research project. This mimics a traditional research project under an advisor's supervision without the undesired drawback of an unknown outcome.