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Full-Text Articles in Physical Sciences and Mathematics
Electronic And Vibrational Spectroscopy Of Ni+(H2o), Jennifer S. Daluz
Electronic And Vibrational Spectroscopy Of Ni+(H2o), Jennifer S. Daluz
Masters Theses 1911 - February 2014
The electronic and vibrational spectra of Ni+(H2O) were measured using photofragment spectroscopy. In the electronic spectrum, photodissociation is observed at photon energies above 16875 cm-1. The only fragment observed is Ni+. The electronic spectrum consists of well-resolved peaks spaced by ~340 cm-1, due to a vibrational progression in the excited electronic state. These peaks have complex sub-structure, consisting of a triplet, spaced by ~30 cm-1. The sub-structure is due to rotational structure in a perpendicular transition of a prolate top molecule. In addition to this major progression, there …
Pharmacological Chaperoning In Fabry Disease, Jerome Rogich
Pharmacological Chaperoning In Fabry Disease, Jerome Rogich
Masters Theses 1911 - February 2014
Fabry Disease is an X-‐linked lysosomal storage disorder characterized by a variety of symptoms including hypohydrosis, seizures, cardiac abnormalities, skin lesions, and chronic pain. These symptoms stem from a lack of functional endogenous α-‐ Galactosidase A (α-GAL), which leads to an accrual of its natural substrate. The severity of the disease symptoms can be directly correlated with the amount of residual enzyme activity. It has been shown that an imino sugar, 1-deoxygalactonojirimycin (DGJ), can increase enzymatic activity and clear excess substrate. This pH-‐dependent chaperoning phenomenon is believed to arise from the presence of aspartic acid 170 in the active site. …
Attenuation Of Acid Mine Drainage Enhanced By Organic Carbon And Limestone Addition: A Process Characterization, Anna M. Gillmor
Attenuation Of Acid Mine Drainage Enhanced By Organic Carbon And Limestone Addition: A Process Characterization, Anna M. Gillmor
Masters Theses 1911 - February 2014
Surface and groundwaters in contact with mining-exposed pyritic materials have the capacity to generate acid mine drainage (AMD), an acidic, sulfate-rich, metals-laden effluent. The Davis Mine located in northwestern Massachusetts offers a model site to study the processes of natural attenuation of acid mine drainage. These include physico-chemical processes such as dilution and sorption, geochemical processes such as aluminosilicate weathering and biological processes such as transformation and cycling of sulfate, iron and acidity by bacterial metabolism. A focus of recent research undertaken at the site has been characterizing the presence and activity of these bacteria with an aim to stimulate …