Physical Sciences and Mathematics Commons^™

Ferrinaphth: A Fluorescent Chemodosimeter For Redox Active Metal Ions, Shawn Burdette, Randy Jackson, Yu Shi, Xudong Yao

Shawn C. Burdette

FerriNaphth, a fluorescent chemodosimeter for FeIII, has been prepared and characterized. The probe consists of a catechol ligand linked to a naphthalimide fluorophore by an aniline nitrogen linker. Upon exposure to FeIII, the aminocatechol of FerriNaphth is oxidized to the corresponding quinone, which in its imine-one tautomer, is hydrolyzed to liberate a fluorescent aminonaphthalimide derivative. The fluorescence behavior is consistent with oxidation being promoted by metal coordination.