Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Publication
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
Effect Of Disulfide Bond Scrambling On Protein Stability, Aggregation, And Cytotoxicity, Colina Dutta
Effect Of Disulfide Bond Scrambling On Protein Stability, Aggregation, And Cytotoxicity, Colina Dutta
Dissertations, Master's Theses and Master's Reports
Proteins are nano-machines that carry out majority of the cellular functions. Thermodynamically they are functional and stable within a very narrow range (1 kcal/mol). External perturbations in the form of pH change, thermal, or oxidative/reducing stress can destabilize the protein resulting in misfolding and aggregation. Prolonged environmental stress can affect the cells adaptive response resulting in loss of ability to refold or recycle proteins. This can lead to accumulation of misfolded or aggregated proteins within the cell. Such accumulation of aggregated proteins have been associated with neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS), Parkinson’s, Huntington’s, and Alzheimer’s disease. There …
Facile Electrochemical Synthesis Of Antimicrobial Tio2 Nanotube Arrays, Yu Zhao, Qi Xing, Jagadeesh Janjanam, Kun He, Fei Long, Ke-Bin Low, Ashutosh Tiwari, Feng Zhao, Reza Shahbazian-Yassar, Tolou Shokuhfar
Facile Electrochemical Synthesis Of Antimicrobial Tio2 Nanotube Arrays, Yu Zhao, Qi Xing, Jagadeesh Janjanam, Kun He, Fei Long, Ke-Bin Low, Ashutosh Tiwari, Feng Zhao, Reza Shahbazian-Yassar, Tolou Shokuhfar
Department of Chemistry Publications
Infection-related complications have been a critical issue for the application of titanium orthopedic implants. The use of Ag nanoparticles offers a potential approach to incorporate antimicrobial properties into the titanium implants. In this work, a novel and simple method was developed for synthesis of Ag (II) oxide deposited TiO2 nanotubes (TiNTs) using electrochemical anodization followed by Ag electroplating processes in the same electrolyte. The quantities of AgO nanoparticles deposited in TiNT were controlled by selecting different electroplating times and voltages. It was shown that AgO nanoparticles were crystalline and distributed throughout the length of the nanotubes. Inductively coupled plasma …