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Articles 1 - 30 of 31
Full-Text Articles in Physical Sciences and Mathematics
Optimization Of Polymer Separation By Gradient Polymer Elution Chromatography, Gideon R. Liem, Linda Nien-Hwa Wang
Optimization Of Polymer Separation By Gradient Polymer Elution Chromatography, Gideon R. Liem, Linda Nien-Hwa Wang
The Summer Undergraduate Research Fellowship (SURF) Symposium
High Performance Liquid Chromatography (HPLC) has been a versatile separation method for polymers for many years. Analysis of different polymers by HPLC is typically done by utilizing the differential solubility of the polymers by mixing a good solvent and an anti-solvent in various compositions. This method is called Gradient Polymer Elution Chromatography (GPEC). While GPEC has been used extensively, it commonly uses a linear gradient to separate components. Linear solvent gradients consume a lot of solvent and take a relatively long time (> 30 minutes) to complete. The goal of this study is to develop a step gradient from a …
Investigating Intermolecular Interactions In Crystalline Aspirin Using Cdft, Nicholas Turner, Tonglei Li, Mingtao Zhang
Investigating Intermolecular Interactions In Crystalline Aspirin Using Cdft, Nicholas Turner, Tonglei Li, Mingtao Zhang
The Summer Undergraduate Research Fellowship (SURF) Symposium
Drugs today are widely administered in their crystalline form, namely via tablets and capsules. The crystal structure of a drug molecule affects important drug qualities such as solubility, bioavailability, shelf life, and compaction properties. In order to form a basis for crystal structure prediction, it is necessary to first understand how intermolecular interactions cause molecules to pack in certain ways. Being able to predict and perhaps even control a drug molecule’s crystal structure will lead to the development of higher quality drugs that perform more consistently. Scientists and engineers do not fully understand the reasons for a molecule assuming a …
Investigation Of Major Intermolecular Interactions In 7,8-Dihydrobenzo(K)Phenanthridin-6(5h)-One Crystal Using Quantum Calculations And Crystallographic Visualization Programs, Zhiwei Liao, Tonglei Li, Mingtao Zhang
Investigation Of Major Intermolecular Interactions In 7,8-Dihydrobenzo(K)Phenanthridin-6(5h)-One Crystal Using Quantum Calculations And Crystallographic Visualization Programs, Zhiwei Liao, Tonglei Li, Mingtao Zhang
The Summer Undergraduate Research Fellowship (SURF) Symposium
Currently, tablets and capsules are the most common ways of delivering drugs. The active pharmaceutical ingredients and excipients used to make those tablets and capsules are in their crystalline form generally. However, a single molecule can form multiple different crystal structures because of different packing arrangements of the molecules. These different crystal structures have identical chemical composition but different properties such as solubility, density, stability, etc. This phenomenon is called polymorphism. Occurrence of polymorphism could be a disaster for both patients and pharmaceutical companies, as the drug could lose its efficacy due to changes in properties. Studying intermolecular interactions in …
Training An Asymmetric Signal Perceptron In An Artificial Chemistry, Peter Banda
Training An Asymmetric Signal Perceptron In An Artificial Chemistry, Peter Banda
Student Research Symposium
Autonomous learning implemented purely by means of a synthetic chemical system has not been previously realized. Learning promotes reusability, and minimizes the system design to simple input-output specification. In this poster, I present a simulated chemical system, the first full-featured implementation of a perceptron in an artificial (simulated) chemistry, which can successfully learn all 14 linearly separable logic functions. A perceptron is the simplest system capable of learning inspired by the functioning of a biological neuron. My newest model called the asymmetric signal perceptron (ASP) is, as opposed to its predecessors such as the weight-race perceptron (WRP), substantially simpler by …
An Alternative Ribozyme For The Rna Hypercycle, Ishak Elkhal
An Alternative Ribozyme For The Rna Hypercycle, Ishak Elkhal
Student Research Symposium
In the quest to forward understanding of the prebiotic world (specifically, the RNA World Hypothesis), one of the most interesting paradigms to consider is the potential for cooperative networks that may have driven molecular evolution forward. Such a network may exist as an RNA hypercycle, as proposed by Eigen (1977). Much progress has been made towards an RNA hypercycle-like system, especially using the Azoarcus ribozyme system demonstrated by Vaidya et al. (2012). The current work is dedicated to constructing a second model as a cooperative RNA network, utilizing a group I intron from Coxiella burnetii (Cbu1917). The intron was constructed …
Development And Characterization Of Multi-Functional Probes For Use With Scanning Electrochemical Microscopy, Jiwon Lee, Colleen Leonard, Melinda Baur, Faculty Advisor
Development And Characterization Of Multi-Functional Probes For Use With Scanning Electrochemical Microscopy, Jiwon Lee, Colleen Leonard, Melinda Baur, Faculty Advisor
John Wesley Powell Student Research Conference
Using Scanning Electrochemical Microscopy (SECM) with electrode probes that make simultaneous current and impedance measurements is useful for analysis of biological substrates. The current and impedance measurements are both dependent upon the proximity to a surface.
Experiments with the single carbon fiber electrodes show that the impedance measurements are independent of the current and applied potential. In order to detect neurotransmitter release from a cell, the electrode must be positioned very close to the cell surface. Impedance-based positioning eliminates the need for addition of biologically toxic redox mediators to position the electrode. Furthermore, it was found that multiple carbon fiber …
Vertebrate Neuronal Chemorepellents, Semaphorin 3c And Netrin-1, Are Chemorepellents In Tetrahymena Thermophila, Caleb Alley, Chris Griffin, Josie Hein, Daniel Kohl, Brad Schmidt, David Yoder, Heather Kuruvilla
Vertebrate Neuronal Chemorepellents, Semaphorin 3c And Netrin-1, Are Chemorepellents In Tetrahymena Thermophila, Caleb Alley, Chris Griffin, Josie Hein, Daniel Kohl, Brad Schmidt, David Yoder, Heather Kuruvilla
The Research and Scholarship Symposium (2013-2019)
No abstract provided.
A Computational Study Of The Vibrational Spectra Of Mono-Nitrated Fluoranthenes, Jorge Ojeda
A Computational Study Of The Vibrational Spectra Of Mono-Nitrated Fluoranthenes, Jorge Ojeda
Undergraduate Research Conference
No abstract provided.
A Determination Of The Aspartame Content In Select Diet Beverages, Jorge Ojeda
A Determination Of The Aspartame Content In Select Diet Beverages, Jorge Ojeda
Undergraduate Research Conference
Millions of dollars are spent every year on diet beverages and there has been much controversy on the contents in these beverages, mainly the artificial sweetener aspartame. It is known that aspartame is included in many diet beverages, but the actual amount of aspartame used is not listed in the nutritional facts or provided by the beverage manufacturers. For this reason, the aspartame content of various soft drinks, Coke Zero, Pepsi Max, Diet Pepsi, and Pepsi Next, was analyzed and compared to a calibration plot utilizing Diet Coke as a standard. Diet Coke was used due to the unavailablity of …
Quantitative Community Geography: A Preliminary Evaluation Of Nitrogen Dioxide Levels And Possible Solutions To Exposure Rates In Npu-V, Atlanta, Ga, Alyssa M. Combs, Maria C. Martinez, Kumar K. Amarnath, Hannah Kaplan, Mary Winsor, Rebecca A. Pickering
Quantitative Community Geography: A Preliminary Evaluation Of Nitrogen Dioxide Levels And Possible Solutions To Exposure Rates In Npu-V, Atlanta, Ga, Alyssa M. Combs, Maria C. Martinez, Kumar K. Amarnath, Hannah Kaplan, Mary Winsor, Rebecca A. Pickering
Georgia State Undergraduate Research Conference
No abstract provided.
Development Of Novel Inhibitors Targeting Epigenetic Enzymes, Johnny Truong, Leilei Yan Dr., Brandon Canup, Kun Qian, George Y. Zheng Dr.
Development Of Novel Inhibitors Targeting Epigenetic Enzymes, Johnny Truong, Leilei Yan Dr., Brandon Canup, Kun Qian, George Y. Zheng Dr.
Georgia State Undergraduate Research Conference
No abstract provided.
Spectroscopic Study Of 4-Methoxychalcone And Human Serum Albumin: Binding Interaction, Rosalind Usher
Spectroscopic Study Of 4-Methoxychalcone And Human Serum Albumin: Binding Interaction, Rosalind Usher
Georgia State Undergraduate Research Conference
No abstract provided.
Synthesis And Evaluation Of Carbocyanine Dyes As Prmt Inhibitors And Imaging Agents, Amber E. Howard
Synthesis And Evaluation Of Carbocyanine Dyes As Prmt Inhibitors And Imaging Agents, Amber E. Howard
Georgia State Undergraduate Research Conference
No abstract provided.
04. Botany, University Of Central Oklahoma
04. Botany, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
02. Animal Science, University Of Central Oklahoma
02. Animal Science, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
05. Chemistry, University Of Central Oklahoma
05. Chemistry, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
03. Biology, University Of Central Oklahoma
03. Biology, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
09. Environmental Science, University Of Central Oklahoma
09. Environmental Science, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
12. Kinesiology, University Of Central Oklahoma
12. Kinesiology, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
07. Criminal Justice, University Of Central Oklahoma
07. Criminal Justice, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
11. Genetics, University Of Central Oklahoma
11. Genetics, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
08. Engineering, University Of Central Oklahoma
08. Engineering, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
15. Pharmacy, University Of Central Oklahoma
15. Pharmacy, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
13. Mathematics, University Of Central Oklahoma
13. Mathematics, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
14. Optometry, University Of Central Oklahoma
14. Optometry, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
16. Physics, University Of Central Oklahoma
16. Physics, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
10. Forensic Science, University Of Central Oklahoma
10. Forensic Science, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
18. Statistics, University Of Central Oklahoma
18. Statistics, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
17. Psychology, University Of Central Oklahoma
17. Psychology, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.
19. Zoology, University Of Central Oklahoma
19. Zoology, University Of Central Oklahoma
Oklahoma Research Day Abstracts
No abstract provided.