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Full-Text Articles in Physical Sciences and Mathematics
Explorations On Non-Covalent Interactions: From Supramolecules To Drug-Like Molecules, Zhanpeng Zhang
Explorations On Non-Covalent Interactions: From Supramolecules To Drug-Like Molecules, Zhanpeng Zhang
USF Tampa Graduate Theses and Dissertations
Non-covalent interactions are everywhere in our material world. From the microstructures of organisms to the functional materials used in industrial production, whenever matter exists, there are non-covalent interactions between the molecules that build up the matter.The exploration of non-covalent forces helps people understand the intrinsic principles of life processes, it can be applied to create new supramolecular materials as well. Supramolecular chemistry is a research field focusing on the properties and applications of non-covalent interactions. Various non-covalent interactions, such as hydrogen bonds, metal-ligand coordination, π-π interaction, hydrophobic interaction, etc., are objects of research in supramolecular chemistry.
Not only supramolecular chemists, …
Self-Assembly Of Metallo-Supramolecules Based On Terpyridine And Its Derivatives, Yu Yan
Self-Assembly Of Metallo-Supramolecules Based On Terpyridine And Its Derivatives, Yu Yan
USF Tampa Graduate Theses and Dissertations
By studying coordination complexes in nature, such as chlorophyll, heme, and Enterobacter, we have learned that the structures of coordination complexes are closely related to their functions. However, it remains a challenge to achieve elaborate structures and sophisticated functions of complexes through synthetic methods. In the supramolecular chemistry field, coordination-driven self-assembly as a bottom-up approach are used to construct diverse supramolecules with well-defined structures and desired functions. The ways to achieve the goal including (1) rearranging components through coordination; (2)linking metal ions and organic frameworks to complete energy transfer; (3) converting between assembly and disassembly due to detection of stimuli. …
Construction Of G-Quadruplexes Via Self-Assembly: Enhanced Stability And Unique Properties, Ying He
Construction Of G-Quadruplexes Via Self-Assembly: Enhanced Stability And Unique Properties, Ying He
USF Tampa Graduate Theses and Dissertations
This dissertation mainly contains three parts: 1) The construction of well-defined G8-octamers through the monomer conformational design. 2) The construction of cross-layer interactions in the G8-octamer for enhanced stability in H-bond competitive solvents. 3) Design and synthesis of 8-triazole guanosine with photoluminescent properties.
Through the structural conformational design, we have developed a new class of guanosine derivatives with modification on guanine (8-aryl) and ribose (2’,3’-isopropylidene). This unique design has led to the formation of the first discrete G8-octamer with structure characterized by NMR, MS and single crystal X-ray diffraction. The selectivity between monovalent (K+) and divalent cat-ions (Ba2+ and Sr2+) …
Metal-Organic Materials: From Design Principles To Practical Applications, Mohamed H. Alkordi
Metal-Organic Materials: From Design Principles To Practical Applications, Mohamed H. Alkordi
USF Tampa Graduate Theses and Dissertations
The works presented herein outline rational design approaches towards construction of solid state materials with great potentials to answer some of current demanding applications. Specifically, the materials targeted are metal−organic materials with desirable structural features and functional properties. Metal−organic materials are constructed from organic linker molecules and metal ions under relatively mild solvothermal reaction conditions that preserve the structural features of the relatively simple building blocks. Therefore, it is feasible to conceive a retrospective pathway of the reaction and thus deconstruct the desirable structures into simple, chemicallyrelevant, building blocks in an approach known as the molecular building block approach. Due …