Physical Sciences and Mathematics Commons^™

Phenyl Functionalized Sol-Gel Silica Sorbent For Capillary Microextraction And Chromia-Based Sol-Gel Ucon Stationary Phase For Capillary Gas Chromatography, Michael M. Mclean

USF Tampa Graduate Theses and Dissertations

The first chapter of this thesis presents an introduction to sol-gel methodology whose usefulness as a synthetic route will be demonstrated with two applications in chromatography. The first application involves the fabrication of a capillary micro-extraction (CME) device by coating a phenyl functionalized extracting phase on the inner surface of a fused silica capillary for analyte pre-concentration. The device was coupled on-line to a RP-HPLC system and practicality was demonstrated using allergens as target analytes. The allergens chosen as model analytes are typically found in fragrance products and food. Most of the 26 fragrance allergens that are monitored by various …