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Full-Text Articles in Physical Sciences and Mathematics
Second Oh Overtone Excitation And Statistical Dissociation Dynamics Of Peroxynitrous Acid, I. M. Konen, E. X.J. Li, Thomas Alex Stephenson, M. I. Lester
Second Oh Overtone Excitation And Statistical Dissociation Dynamics Of Peroxynitrous Acid, I. M. Konen, E. X.J. Li, Thomas Alex Stephenson, M. I. Lester
Chemistry & Biochemistry Faculty Works
The second OH overtone transition of the trans-perp conformer of peroxynitrous acid (tp-HOONO) is identified using infrared action spectroscopy. HOONO is produced by the recombination of photolytically generated OH and NO(2) radicals, and then cooled in a pulsed supersonic expansion. The second overtone transition is assigned to tp-HOONO based on its vibrational frequency (10 195.3 cm(-1)) and rotational band contour, which are in accord with theoretical predictions and previous observations of the first overtone transition. The transition dipole moment associated with the overtone transition is rotated considerably from the OH bond axis, as evident from its hybrid band composition, indicating …
Amyloid-Β Protofibrils Differ From Amyloid-Β Aggregates Induced In Dilute Hexafluoroisopropanol In Stability And Morphology, Michael Nichols, Melissa Moss, Dana Reed, Stephanie Cratic-Mcdaniel, Jan Hoh, Terrone Rosenberry
Amyloid-Β Protofibrils Differ From Amyloid-Β Aggregates Induced In Dilute Hexafluoroisopropanol In Stability And Morphology, Michael Nichols, Melissa Moss, Dana Reed, Stephanie Cratic-Mcdaniel, Jan Hoh, Terrone Rosenberry
Chemistry & Biochemistry Faculty Works
The brains of Alzheimer’s disease (AD) patients contain large numbers of amyloid plaques that are rich in fibrils composed of 40- and 42-residue amyloid-β (Aβ) peptides. Several lines of evidence indicate that fibrillar Aβ and especially soluble Aβ aggregates are important in the etiology of AD. Recent reports also stress that amyloid aggregates are polymorphic and that a single polypeptide can fold into multiple amyloid conformations. Here we demonstrate that Aβ-(1–40) can form soluble aggregates with predominant β-structures that differ in stability and morphology. One class of aggregates involved soluble Aβ protofibrils, prepared by vigorous overnight agitation of monomeric Aβ-(1–40) …
Response To "Kinetic And Mechanistic Studies Of The Recombination Of Oh With No2: Vibrational Deactivation, Isotopic Scrambling And Product Isomer Branching Ratios", J. Stutz, A. R. Ravishankara, J. A. Pyle, A. Tuck, M. J. Evans, H. Herrmann, M. P. Chipperfield, R. Zellner, H. Roscoe, D. E. Shallcross, R. A. Cox, P. S. Monks, S. R. Arnold, D. S. Stevenson, D. E. Heard, J. J. Remedios, R. P. Wayne, E. A. Cohen, T. Brauers, A. J. Orr-Ewing, M. A. Blitz, L. Wang, G. Duxbury, T. Dibble, C. A. Taatjes, W. Eisfeld, P. W. Seakins, A. Kovács, S. Dóbé, E. Farkas, T. Ingham, D. Rowley, C. E. Kolb, Thomas Alex Stephenson, A. J. Hynes, N. M. Donahue, I. W. M. Smith, D. Self, D. J. Donaldson
Response To "Kinetic And Mechanistic Studies Of The Recombination Of Oh With No2: Vibrational Deactivation, Isotopic Scrambling And Product Isomer Branching Ratios", J. Stutz, A. R. Ravishankara, J. A. Pyle, A. Tuck, M. J. Evans, H. Herrmann, M. P. Chipperfield, R. Zellner, H. Roscoe, D. E. Shallcross, R. A. Cox, P. S. Monks, S. R. Arnold, D. S. Stevenson, D. E. Heard, J. J. Remedios, R. P. Wayne, E. A. Cohen, T. Brauers, A. J. Orr-Ewing, M. A. Blitz, L. Wang, G. Duxbury, T. Dibble, C. A. Taatjes, W. Eisfeld, P. W. Seakins, A. Kovács, S. Dóbé, E. Farkas, T. Ingham, D. Rowley, C. E. Kolb, Thomas Alex Stephenson, A. J. Hynes, N. M. Donahue, I. W. M. Smith, D. Self, D. J. Donaldson
Chemistry & Biochemistry Faculty Works
No abstract provided.