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Physical Sciences and Mathematics Commons

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Biostatistics

Selected Works

2009

Bioinformatics and Neuroinformatics

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Full-Text Articles in Physical Sciences and Mathematics

Assessing Time-Dependent Association Between Scalp Eeg And Muscle Activation: A Functional Random-Effects Model Approach, Xiao-Feng Wang, Qi Yang, Zhaozhi Fan, Chang-Kai Sun, Guang H. Yue Feb 2009

Assessing Time-Dependent Association Between Scalp Eeg And Muscle Activation: A Functional Random-Effects Model Approach, Xiao-Feng Wang, Qi Yang, Zhaozhi Fan, Chang-Kai Sun, Guang H. Yue

Xiaofeng Wang

This study investigates time-dependent associations between source strength estimated from high-density scalp electroencephalogram (EEG) and force of voluntary handgrip contraction at different intensity levels. We first estimate source strength from raw EEG signals collected during voluntary muscle contractions at different levels and then propose a functional random-effects model approach in which both functional fixed effects and functional random-effects are considered for the data. Two estimation procedures for the functional model are discussed. The first estimation procedure is a two-step method which involves no iterations. It can flexibly use different smoothing methods and smoothing parameters. The second estimation procedure benefits from …