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Physical Sciences and Mathematics Commons™
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Biochemistry, Biophysics, and Structural Biology
UNLV Theses, Dissertations, Professional Papers, and Capstones
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- Beryllium (1)
- Beryllium compounds (1)
- Catenin (1)
- Clostridium difficile (1)
- Clostridium difficile associated diarrhea (1)
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- Environmental decontamination (1)
- Glycogen Synthase Kinase - 3β (1)
- Glycogen synthase kinase-3 (1)
- Healthcare associated infection (1)
- Lithium (1)
- Lithium chloride (1)
- Phosphorylation (1)
- Protein-tyrosine kinase – Inhibitors (1)
- Real-time polymerase chain reaction (1)
- Ser-9 phosphorylation (1)
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- Surface sampling (1)
- Β-Catenin (1)
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
The Presence Of Clostridium Difficile On Environmental Surfaces In Healthcare Facilities Pre- And Post-Decontamination Of Patient Rooms, Theresa Trice
The Presence Of Clostridium Difficile On Environmental Surfaces In Healthcare Facilities Pre- And Post-Decontamination Of Patient Rooms, Theresa Trice
UNLV Theses, Dissertations, Professional Papers, and Capstones
Healthcare-associated infections (HAIs) are infections related to receiving medical care. HAIs are responsible for an excess of morbidity and mortality among hospitalized patients. Though most HAIs rates are on the decline, Clostridium difficile infection rates are at an all-time high, primarily due to the persistence of C. difficile spores in the environment. In the United States, Clostridium difficile-related mortality rates per million have increased from 5.7 in 1999 to 23.7 in 2004, with an estimated 26,642 deaths due to Clostridium difficile infections (CDIs). Clostridium difficile is transmitted via the fecal-oral route or aerosolized endospores, but it can also be transmitted …
Beryllium Is A Potent And Unique Gsk-3Β Inhibitor With Potential To Differentially Regulate Glycogen Synthase And Β-Catenin, Ata Ur Rahman Mohammed Abdul
Beryllium Is A Potent And Unique Gsk-3Β Inhibitor With Potential To Differentially Regulate Glycogen Synthase And Β-Catenin, Ata Ur Rahman Mohammed Abdul
UNLV Theses, Dissertations, Professional Papers, and Capstones
Glycogen Synthase Kinase-3β (GSK-3β) is an important serine/threonine kinase that phosphorylates/regulates diverse and metabolically important proteins. Some of the important substrates of GSK-3β are glycogen synthase, tau, β-catenin, cyclin D1, axin, c-jun, c-myc, Heat Shock Factor–1, BCL-3, CREB, Histone H1.5, mdm2, p21 (CIP1), pyruvate dehydrogenase and many more. De-regulation of GSK-3β has been implicated in diseases like cancer, Alzheimer’s disease, bipolar disorder and type 2 diabetes mellitus. Currently, GSK-3β is one of the most widely studied proteins and there is a great interest in developing potent and efficient GSK-3β-inhibitors for research as well as therapeutic purposes. We demonstrate that beryllium …