Physical Sciences and Mathematics Commons^™

Towards A Rapid Screening Of Liver Grafts At The Operating Room Using Mid-Infrared Spectroscopy, David Perezguaita, Marta Moreno Torres, Ramiro Jover, Eugenia Pareja, Bernard Lendl, Julia Kuligowsky, Guillermo Quintas

Articles

The estimation of steatosis in a liver graft is mandatory prior to liver transplantation, as the risk of graft failure increases with the level of infiltrated fat. However, the assessment of liver steatosis before transplantation is typically based on a qualitative or semiquantitative characterization by visual inspection and palpation and histological analysis. Thus, there is an unmet need for transplantation surgeons to have access to a diagnostic tool enabling an in situ fast classification of grafts prior to extraction. In this study, we have assessed an attenuated total reflection−Fourier transform infrared (ATR−FTIR) spectroscopic method compatible with the requirements of an …