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Full-Text Articles in Physical Sciences and Mathematics

Regulating New Tech: Problems, Pathways, And People, Cary Coglianese Dec 2021

Regulating New Tech: Problems, Pathways, And People, Cary Coglianese

All Faculty Scholarship

New technologies bring with them many promises, but also a series of new problems. Even though these problems are new, they are not unlike the types of problems that regulators have long addressed in other contexts. The lessons from regulation in the past can thus guide regulatory efforts today. Regulators must focus on understanding the problems they seek to address and the causal pathways that lead to these problems. Then they must undertake efforts to shape the behavior of those in industry so that private sector managers focus on their technologies’ problems and take actions to interrupt the causal pathways. …


Statistical Potentials For Rna-Protein Interactions Optimized By Cma-Es, Takayuki Kimura, Nobuaki Yasuo, Masakazu Sekijima, Brooke Lustig Oct 2021

Statistical Potentials For Rna-Protein Interactions Optimized By Cma-Es, Takayuki Kimura, Nobuaki Yasuo, Masakazu Sekijima, Brooke Lustig

Faculty Research, Scholarly, and Creative Activity

Characterizing RNA-protein interactions remains an important endeavor, complicated by the difficulty in obtaining the relevant structures. Evaluating model structures via statistical potentials is in principle straight-forward and effective. However, given the relatively small size of the existing learning set of RNA-protein complexes optimization of such potentials continues to be problematic. Notably, interaction-based statistical potentials have problems in addressing large RNA-protein complexes. In this study, we adopted a novel strategy with covariance matrix adaptation (CMA-ES) to calculate statistical potentials, successfully identifying native docking poses.


Artificial Intelligence In Cyber Security, University Of Maine Artificial Intelligence Initiative Sep 2021

Artificial Intelligence In Cyber Security, University Of Maine Artificial Intelligence Initiative

General University of Maine Publications

UMaine AI draws top talent and leverages a distinctive set of capabilities from the University of Maine and other collaborating institutions from across Maine and beyond, while it also recruits world-class talent from across the nation and the world. It is centered at the University of Maine, leveraging the university’s strengths across disciplines, including computing and information sciences, engineering, health and life sciences, business, education, social sciences, and more.


Cognition-Enhanced Machine Learning For Better Predictions With Limited Data, Florian Sense, Ryan Wood, Michael G. Collins, Joshua Fiechter, Aihua W. Wood, Michael Krusmark, Tiffany Jastrzembski, Christopher W. Myers Sep 2021

Cognition-Enhanced Machine Learning For Better Predictions With Limited Data, Florian Sense, Ryan Wood, Michael G. Collins, Joshua Fiechter, Aihua W. Wood, Michael Krusmark, Tiffany Jastrzembski, Christopher W. Myers

Faculty Publications

The fields of machine learning (ML) and cognitive science have developed complementary approaches to computationally modeling human behavior. ML's primary concern is maximizing prediction accuracy; cognitive science's primary concern is explaining the underlying mechanisms. Cross-talk between these disciplines is limited, likely because the tasks and goals usually differ. The domain of e-learning and knowledge acquisition constitutes a fruitful intersection for the two fields’ methodologies to be integrated because accurately tracking learning and forgetting over time and predicting future performance based on learning histories are central to developing effective, personalized learning tools. Here, we show how a state-of-the-art ML model can …


Orthogonal Inductive Matrix Completion, Antoine Ledent, Rrodrigo Alves, Marius Kloft Sep 2021

Orthogonal Inductive Matrix Completion, Antoine Ledent, Rrodrigo Alves, Marius Kloft

Research Collection School Of Computing and Information Systems

We propose orthogonal inductive matrix completion (OMIC), an interpretable approach to matrix completion based on a sum of multiple orthonormal side information terms, together with nuclear-norm regularization. The approach allows us to inject prior knowledge about the singular vectors of the ground-truth matrix. We optimize the approach by a provably converging algorithm, which optimizes all components of the model simultaneously. We study the generalization capabilities of our method in both the distribution-free setting and in the case where the sampling distribution admits uniform marginals, yielding learning guarantees that improve with the quality of the injected knowledge in both cases. As …


Diagnostic Accuracy Of Machine Learning Models To Identify Congenital Heart Disease: A Meta-Analysis, Zahra Hoodbhoy, Uswa Jiwani, Saima Sattar, Rehana A. Salam, Babar Hasan, Jai K. Das Jul 2021

Diagnostic Accuracy Of Machine Learning Models To Identify Congenital Heart Disease: A Meta-Analysis, Zahra Hoodbhoy, Uswa Jiwani, Saima Sattar, Rehana A. Salam, Babar Hasan, Jai K. Das

Department of Paediatrics and Child Health

Background: With the dearth of trained care providers to diagnose congenital heart disease (CHD) and a surge in machine learning (ML) models, this review aims to estimate the diagnostic accuracy of such models for detecting CHD.
Methods: A comprehensive literature search in the PubMed, CINAHL, Wiley Cochrane Library, and Web of Science databases was performed. Studies that reported the diagnostic ability of ML for the detection of CHD compared to the reference standard were included. Risk of bias assessment was performed using Quality Assessment for Diagnostic Accuracy Studies-2 tool. The sensitivity and specificity results from the studies were used to …


Algebraic Graph-Assisted Bidirectional Transformers For Molecular Property Prediction, Dong Chen, Kaifu Gao, Duc Duy Nguyen, Xin Chen, Yi Jiang, Guo-Wei Wei, Feng Pan Jun 2021

Algebraic Graph-Assisted Bidirectional Transformers For Molecular Property Prediction, Dong Chen, Kaifu Gao, Duc Duy Nguyen, Xin Chen, Yi Jiang, Guo-Wei Wei, Feng Pan

Mathematics Faculty Publications

The ability of molecular property prediction is of great significance to drug discovery, human health, and environmental protection. Despite considerable efforts, quantitative prediction of various molecular properties remains a challenge. Although some machine learning models, such as bidirectional encoder from transformer, can incorporate massive unlabeled molecular data into molecular representations via a self-supervised learning strategy, it neglects three-dimensional (3D) stereochemical information. Algebraic graph, specifically, element-specific multiscale weighted colored algebraic graph, embeds complementary 3D molecular information into graph invariants. We propose an algebraic graph-assisted bidirectional transformer (AGBT) framework by fusing representations generated by algebraic graph and bidirectional transformer, as well as …


Artificial Intelligence For Agriculture, University Of Maine Artificial Intelligence Initiative Apr 2021

Artificial Intelligence For Agriculture, University Of Maine Artificial Intelligence Initiative

General University of Maine Publications

UMaine AI draws top talent and leverages a distinctive set of capabilities from the University of Maine and other collaborating institutions from across Maine and beyond, while it also recruits world-class talent from across the nation and the world. It is centered at the University of Maine, leveraging the university’s strengths across disciplines, including computing and information sciences, engineering, health and life sciences, business, education, social sciences, and more.


Development Of A Real-Time Single-Lead Single-Beat Frequency-Independent Myocardial Infarction Detector, Harold Martin Mar 2021

Development Of A Real-Time Single-Lead Single-Beat Frequency-Independent Myocardial Infarction Detector, Harold Martin

FIU Electronic Theses and Dissertations

The central aim of this research is the development and deployment of a novel multilayer machine learning design with unique application for the diagnosis of myocardial infarctions (MIs) from individual heartbeats of single-lead electrocardiograms (EKGs) irrespective of their sampling frequencies over a given range. To the best of our knowledge, this design is the first to attempt inter-patient myocardial infarction detection from individual heartbeats of single-lead (lead II) electrocardiograms that achieves high accuracy and near real-time diagnosis. The processing time of 300 milliseconds to a diagnosis is just at the time range in between extremely fast heartbeats of around 300 …


Manufacturing And Materials, University Of Maine Artificial Intelligence Initiative Mar 2021

Manufacturing And Materials, University Of Maine Artificial Intelligence Initiative

General University of Maine Publications

UMaine AI draws top talent and leverages a distinctive set of capabilities from the University of Maine and other collaborating institutions from across Maine and beyond, while it also recruits world-class talent from across the nation and the world. It is centered at the University of Maine, leveraging the university’s strengths across disciplines, including computing and information sciences, engineering, health and life sciences, business, education, social sciences, and more.


Interpretable, Not Black-Box, Artificial Intelligence Should Be Used For Embryo Selection, Michael Anis Mihdi Afnan, Yanhe Liu, Vincent Conitzer, Cynthia Rudin, Abhishek Mishra, Julian Savulescu, Masoud Afnan Jan 2021

Interpretable, Not Black-Box, Artificial Intelligence Should Be Used For Embryo Selection, Michael Anis Mihdi Afnan, Yanhe Liu, Vincent Conitzer, Cynthia Rudin, Abhishek Mishra, Julian Savulescu, Masoud Afnan

Research outputs 2014 to 2021

Artificial intelligence (AI) techniques are starting to be used in IVF, in particular for selecting which embryos to transfer to the woman. AI has the potential to process complex data sets, to be better at identifying subtle but important patterns, and to be more objective than humans when evaluating embryos. However, a current review of the literature shows much work is still needed before AI can be ethically implemented for this purpose. No randomized controlled trials (RCTs) have been published, and the efficacy studies which exist demonstrate that algorithms can broadly differentiate well between ‘good-’ and ‘poor-’ quality embryos but …


Stock Trend Prediction Using Candlestick Charting And Ensemble Machine Learning Techniques With A Novelty Feature Engineering Scheme, Yaohu Lin, Shancun Liu, Haijun Yang, Harris Wu Jan 2021

Stock Trend Prediction Using Candlestick Charting And Ensemble Machine Learning Techniques With A Novelty Feature Engineering Scheme, Yaohu Lin, Shancun Liu, Haijun Yang, Harris Wu

Information Technology & Decision Sciences Faculty Publications

Stock market forecasting is a knotty challenging task due to the highly noisy, nonparametric, complex and chaotic nature of the stock price time series. With a simple eight-trigram feature engineering scheme of the inter-day candlestick patterns, we construct a novel ensemble machine learning framework for daily stock pattern prediction, combining traditional candlestick charting with the latest artificial intelligence methods. Several machine learning techniques, including deep learning methods, are applied to stock data to predict the direction of the closing price. This framework can give a suitable machine learning prediction method for each pattern based on the trained results. The investment …


Improving Stock Trading Decisions Based On Pattern Recognition Using Machine Learning Technology, Yaohu Lin, Shancun Liu, Haijun Yang, Harris Wu, Bingbing Jiang Jan 2021

Improving Stock Trading Decisions Based On Pattern Recognition Using Machine Learning Technology, Yaohu Lin, Shancun Liu, Haijun Yang, Harris Wu, Bingbing Jiang

Information Technology & Decision Sciences Faculty Publications

PRML, a novel candlestick pattern recognition model using machine learning methods, is proposed to improve stock trading decisions. Four popular machine learning methods and 11 different features types are applied to all possible combinations of daily patterns to start the pattern recognition schedule. Different time windows from one to ten days are used to detect the prediction effect at different periods. An investment strategy is constructed according to the identified candlestick patterns and suitable time window. We deploy PRML for the forecast of all Chinese market stocks from Jan 1, 2000 until Oct 30, 2020. Among them, the data from …


Contracting For Algorithmic Accountability, Cary Coglianese, Erik Lampmann Jan 2021

Contracting For Algorithmic Accountability, Cary Coglianese, Erik Lampmann

All Faculty Scholarship

As local, state, and federal governments increase their reliance on artificial intelligence (AI) decision-making tools designed and operated by private contractors, so too do public concerns increase over the accountability and transparency of such AI tools. But current calls to respond to these concerns by banning governments from using AI will only deny society the benefits that prudent use of such technology can provide. In this Article, we argue that government agencies should pursue a more nuanced and effective approach to governing the governmental use of AI by structuring their procurement contracts for AI tools and services in ways that …


Advancing Cyanobacteria Biomass Estimation From Hyperspectral Observations: Demonstrations With Hico And Prisma Imagery, Ryan E. O'Shea, Nima Pahlevan, Brandon Smith, Mariano Bresciani, Todd Egerton, Claudia Giardino, Lin Li, Tim Moore, Antonio Ruiz-Verdu, Steve Ruberg, Stefan G.H. Simis, Richard Stumpf, Diana Vaičiūtė Jan 2021

Advancing Cyanobacteria Biomass Estimation From Hyperspectral Observations: Demonstrations With Hico And Prisma Imagery, Ryan E. O'Shea, Nima Pahlevan, Brandon Smith, Mariano Bresciani, Todd Egerton, Claudia Giardino, Lin Li, Tim Moore, Antonio Ruiz-Verdu, Steve Ruberg, Stefan G.H. Simis, Richard Stumpf, Diana Vaičiūtė

Biological Sciences Faculty Publications

Retrieval of the phycocyanin concentration (PC), a characteristic pigment of, and proxy for, cyanobacteria biomass, from hyperspectral satellite remote sensing measurements is challenging due to uncertainties in the remote sensing reflectance (∆Rrs) resulting from atmospheric correction and instrument radiometric noise. Although several individual algorithms have been proven to capture local variations in cyanobacteria biomass in specific regions, their performance has not been assessed on hyperspectral images from satellite sensors. Our work leverages a machine-learning model, Mixture Density Networks (MDNs), trained on a large (N = 939) dataset of collocated in situ chlorophyll-a concentrations (Chla), …


Continuity Of Chen-Fliess Series For Applications In System Identification And Machine Learning, Rafael Dahmen, W. Steven Gray, Alexander Schmeding Jan 2021

Continuity Of Chen-Fliess Series For Applications In System Identification And Machine Learning, Rafael Dahmen, W. Steven Gray, Alexander Schmeding

Electrical & Computer Engineering Faculty Publications

Model continuity plays an important role in applications like system identification, adaptive control, and machine learning. This paper provides sufficient conditions under which input-output systems represented by locally convergent Chen-Fliess series are jointly continuous with respect to their generating series and as operators mapping a ball in an Lp-space to a ball in an Lq-space, where p and q are conjugate exponents. The starting point is to introduce a class of topological vector spaces known as Silva spaces to frame the problem and then to employ the concept of a direct limit to describe convergence. The proof of the main …


Deapsecure Computational Training For Cybersecurity Students: Improvements, Mid-Stage Evaluation, And Lessons Learned, Wirawan Purwanto, Yuming He, Jewel Ossom, Qiao Zhang, Liuwan Zhu, Karina Arcaute, Masha Sosonkina, Hongyi Wu Jan 2021

Deapsecure Computational Training For Cybersecurity Students: Improvements, Mid-Stage Evaluation, And Lessons Learned, Wirawan Purwanto, Yuming He, Jewel Ossom, Qiao Zhang, Liuwan Zhu, Karina Arcaute, Masha Sosonkina, Hongyi Wu

University Administration Publications

DeapSECURE is a non-degree computational training program that provides a solid high-performance computing (HPC) and big-data foundation for cybersecurity students. DeapSECURE consists of six modules covering a broad spectrum of topics such as HPC platforms, big-data analytics, machine learning, privacy-preserving methods, and parallel programming. In the second year of this program, to improve the learning experience, we implemented a number of changes, such as grouping modules into two broad categories, "big-data" and "HPC"; creating a single cybersecurity storyline across the modules; and introducing post-workshop (optional) "hackshops." Two major goals of these changes are, firstly, to effectively engage students to maintain …