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Sparsity Regularization In Diffuse Optical Tomography, John Cooper

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The purpose of this dissertation is to improve image reconstruction in Diffuse Optical Tomography (DOT), a high contrast imaging modality that uses a near infrared light source. Because the scattering and absorption of a tumor varies significantly from healthy tissue, a reconstructed spatial representation of these parameters serves as tomographic image of a medium. However, the high scatter and absorption of the optical source also causes the inverse problem to be severely ill posed, and currently only low resolution reconstructions are possible, particularly when using an unmodulated direct current (DC) source.
In this work, the well posedness of the forward …