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Full-Text Articles in Physical Sciences and Mathematics
Modeling Immune System Dynamics During Hiv Infection And Treatment With Differential Equations, Nicole Rychagov
Modeling Immune System Dynamics During Hiv Infection And Treatment With Differential Equations, Nicole Rychagov
CODEE Journal
An inquiry-based project that discusses immune system dynamics during HIV infection using differential equations is presented. The complex interactions between healthy T-cells, latently infected T-cells, actively infected T-cells, and the HIV virus are modeled using four nonlinear differential equations. The model is adapted to simulate long term HIV dynamics, including the AIDS state, and is used to simulate the long term effects of the traditional antiretroviral therapy (ART). The model is also used to test viral rebound over time of combined application of ART and a new drug that blocks the reactivation of the viral genome in the infected cells …
Maintaining Ecosystem And Economic Structure In A Three-Species Dynamical System In Chesapeake Bay, Maila Hallare, Iordanka Panayotova
Maintaining Ecosystem And Economic Structure In A Three-Species Dynamical System In Chesapeake Bay, Maila Hallare, Iordanka Panayotova
CODEE Journal
We consider a three-species fish dynamical system in Chesapeake Bay consisting of the Atlantic menhaden as the prey and its two competing predators, the striped bass and the catfish. Building on our previous work in this system, we consider the issue of balancing economic harvesting goals (financial gain for fishermen) with ecological harvesting goals (non-extinction of species). In particular, we investigate the bionomic equilibria, maximum sustainable yield, and the maximum economic yield. Analytical computations and numerical simulations are employed to provide some mathematical guidance on fisheries management policies.