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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Theoretical Analysis Of Nonlinear Differential Equations, Emily Jean Weymier Feb 2018

Theoretical Analysis Of Nonlinear Differential Equations, Emily Jean Weymier

Electronic Theses and Dissertations

Nonlinear differential equations arise as mathematical models of various phenomena. Here, various methods of solving and approximating linear and nonlinear differential equations are examined. Since analytical solutions to nonlinear differential equations are rare and difficult to determine, approximation methods have been developed. Initial and boundary value problems will be discussed. Several linear and nonlinear techniques to approximate or solve the linear or nonlinear problems are demonstrated. Regular and singular perturbation theory and Magnus expansions are our particular focus. Each section offers several examples to show how each technique is implemented along with the use of visuals to demonstrate the accuracy, …


Analytical Approaches To Improve Accuracy In Solving The Protein Topology Problem, Kamal Al Nasr, Feras Yousef, Ruba Jebril, Christopher Jones Jan 2018

Analytical Approaches To Improve Accuracy In Solving The Protein Topology Problem, Kamal Al Nasr, Feras Yousef, Ruba Jebril, Christopher Jones

Computer Science Faculty Research

To take advantage of recent advances in genomics and proteomics it is critical that the three-dimensional physical structure of biological macromolecules be determined. Cryo-Electron Microscopy (cryo-EM) is a promising and improving method for obtaining this data, however resolution is often not sufficient to directly determine the atomic scale structure. Despite this, information for secondary structure locations is detectable. De novo modeling is a computational approach to modeling these macromolecular structures based on cryo-EM derived data. During de novo modeling a mapping between detected secondary structures and the underlying amino acid sequence must be identified. DP-TOSS (Dynamic Programming for determining the …