Physical Sciences and Mathematics Commons^™

Development Of Novel Analytical Methods With The Aim Of Forensic Analyte Detection Using Ultra-Thin Layer Chromatography, Surface Enhanced Raman Spectroscopy, And Magneto-Elastic Wire Sensing, Nichole Ann Crane

Doctoral Dissertations

The purpose of this dissertation is to develop analytical methods that aid in the detection of forensic analytes. Forensic analytes require methods with increased sensitivity and low limit of detection capabilities. Improvements in separation techniques, surface enhanced Raman spectroscopic techniques, and wire-less gas sensing can each assist in the detection of trace evidence.

When surface enhanced Raman is coupled with thin-layer chromatography a mixture of compounds can be separated and transferred to a metal substrate to be detected using Raman spectroscopy. Surface enhanced Raman scattering enhances the Raman signal intensity by placing a metal substrate in close proximity to an …