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- ALE (1)
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Articles 1 - 4 of 4
Full-Text Articles in Biomedical Informatics
Genome-Scale Methylation Analysis In Blood And Tumor Identifies Immune Profile, Age Acceleration, And Dna Methylation Alterations Associated With Bladder Cancer Outcomes, Ji-Qing Chen
Dartmouth College Ph.D Dissertations
Bladder cancer patients receive frequent screening due to the high tumor recurrence rate (more than 60%). Nowadays, the conventional monitoring method relies on cystoscopy which is highly invasive and increases patient morbidity and burden to the health care system with frequent follow-up. As a result, it is urgent to explore novel markers related to the outcomes of bladder cancer. Immune profiles have been associated with cancer outcomes and may have the potential to be biomarkers for outcomes management. However, little work has been conducted to investigate the associations of immune cell profiles with bladder cancer outcomes. Here, I utilized the …
Evidence Assisted Learning For Clinical Decision Support Systems, Bhanu Pratap Singh Rawat
Evidence Assisted Learning For Clinical Decision Support Systems, Bhanu Pratap Singh Rawat
Doctoral Dissertations
Clinical decision support systems (CDSS) provide intelligently filtered knowledge and patient-specific and population information to the clinicians, nursing staff and healthcare professionals. CDSS can significantly improve the quality, safety, efficiency and effectiveness of health care. Over the last decade, American hospitals have adopted electronic health records (EHRs) widely resulting in a massive collection of clinical notes such as admission notes, physician notes, nursing notes and discharge summaries. For the past couple of decades, most of the work in CDSS has been focused on developing knowledge-based systems using structured data such as medications and ICD codes. In contrast, the EHR notes …
Meta-Analytic Connectivity Modelling Of Healthy Swallowing, Chris R. Tilton
Meta-Analytic Connectivity Modelling Of Healthy Swallowing, Chris R. Tilton
Honors Theses and Capstones
A quantitative, voxel-wise meta-analysis was performed to investigate the brain regions involved in healthy human swallowing. Studies included in the meta-analysis (1) examined water swallowing, saliva swallowing, or both, (2) included healthy, normal subjects, and (3) reported stereotaxic brain activation coordinates in standard space. Following these criteria, a systematic literature review identified 8 studies that met the criteria. An activation likelihood estimation (ALE) meta-analysis and meta-analytic connectivity modelling (MACM) analysis were performed with BrainMap software. Ten clusters with high activation likelihood were found in the bilateral precentral gyri, right insula, left declive, right medial frontal gyrus, right dorsal nucleus of …
Uncovering The Role Of Fat-Infiltrated Axillary Lymph Nodes In Obesity-Related Diseases With Statistical And Machine Learning Analyses, Qingyuan Song
Uncovering The Role Of Fat-Infiltrated Axillary Lymph Nodes In Obesity-Related Diseases With Statistical And Machine Learning Analyses, Qingyuan Song
Dartmouth College Ph.D Dissertations
The link between obesity and pathogenesis is a complex and multifaceted area of research that is yet to be fully understood. Ample evidence exists to demonstrate the direct relationship between excessive internal fat and various health conditions such as cancer, and metabolic and cardiovascular diseases. The infiltration of ectopic fat into axillary lymph nodes, observable on breast cancer screening images, has been shown to be correlated with body mass index (BMI) in women undergoing screening. This study aimed to explore the relationship between fat-infiltrated axillary lymph nodes (FIN) and obesity-related diseases, with the goal of evaluating the clinical value of …