Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Using The Commons To Facilitate Health Communication, Anna Liebzeit, Karen Adams, Mat Jakobi
Using The Commons To Facilitate Health Communication, Anna Liebzeit, Karen Adams, Mat Jakobi
Aboriginal Policy Research Consortium International (APRCi)
No abstract provided.
Lesion Of Cholinergic Neurons In Nucleus Basalis Enhances Response To General Anesthetics, Leung L. Stan
Lesion Of Cholinergic Neurons In Nucleus Basalis Enhances Response To General Anesthetics, Leung L. Stan
Physiology and Pharmacology Publications
Acetylcholine in the brain has been associated with consciousness and general anesthesia effects. We tested the hypothesis that the integrity of the nucleus basalis magnocellularis (NBM) affects the response to general anesthetics. Cholinergic neurons in NBM were selectively lesioned by bilateral infusion of 192IgG-saporin in adult, male Long–Evans rats, and control rats were infused with saline. Depletion of choline-acetyltransferase (ChAT)-immunoreactive cells in the NBM and decrease in optical density of acetylcholinesterase (AChE) staining in the frontal and visual cortices confirmed a significant decrease in NBM cholinergic neurons in lesioned as compared to control rats. AChE staining in the hippocampus and …