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Full-Text Articles in Medicine and Health Sciences

Functional Capacity Profiles In Bipolar Disorder And Schizophrenia, Ashley Sara Emami Aug 2020

Functional Capacity Profiles In Bipolar Disorder And Schizophrenia, Ashley Sara Emami

UNLV Theses, Dissertations, Professional Papers, and Capstones

Serious mental illnesses (SMIs) often have an onset early in life and go on to produce disability and functional impairment, which require ongoing supportive services and loss of productivity. Bipolar disorder (BD) and schizophrenia (SZ) are two of the most common SMIs. BD and SZ differ in their pattern of neurocognitive performance, which suggests differences in the severity of functional impairment between the illness groups. Within these psychiatric illness groups, subgroups may also be identified using cluster analysis. Evidence points to heterogeneity in functional outcomes in BD and SZ, yet very little research has assessed for subgroups based on functional …


Psychosis, Spirituality & Expressive Arts Therapy: A Literature Review, Julie Sousa May 2020

Psychosis, Spirituality & Expressive Arts Therapy: A Literature Review, Julie Sousa

Expressive Therapies Capstone Theses

This literature review explores varied treatment modalities for individuals who experience psychosis, carrying diagnoses such as schizophrenia, schizoaffective, bipolar I, or bipolar II. These individuals frequently experience marginalization and stigmatization in society. Unfortunately, this is often mirrored within the health care systems that provide treatment. These systems tend to focus heavily on symptoms, highly pathologizing client’s experiences, which can cause resistance to treatment. While psychopharmacology and traditional talk therapy are shown to be effective, they are not always sustainable. Varied treatment modalities are necessary. In order to promote more holistic treatment for these individuals, this literature review highlights recent global …


Deviant Cortical Sulcation Related To Schizophrenia And Cognitive Deficits In The Second Trimester, Michael Lloyd Mackinley, Priyadharshini Sabesan, Lena Palaniyappan Jan 2020

Deviant Cortical Sulcation Related To Schizophrenia And Cognitive Deficits In The Second Trimester, Michael Lloyd Mackinley, Priyadharshini Sabesan, Lena Palaniyappan

Brain and Mind Institute Researchers' Publications

Aberrant cortical development, inferred from cortical folding, is linked to the risk of schizophrenia. Cortical folds develop in a time-locked fashion during fetal growth. We leveraged this temporal specificity of sulcation to investigate the timing of the prenatal insult linked to schizophrenia and the cognitive impairment seen in this illness. Anatomical MRI scans from 68 patients with schizophrenia and 72 controls were used to evaluate the sulcal depth of five major invariable primary sulci representing lobar development (calcarine sulcus, superior temporal sulcus, superior frontal sulcus, intraparietal sulcus and inferior frontal sulcus) with formation representing the distinct developmental periods. A repeated-measure …